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2004-2005 Fluids & Electolytes Pharmacology Review 9 June 2016 7:16 AM
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Acebutolol Sympatholytic 1 adrenergic antagonist Class II antiarrhythmic Antihypertensive Antianginal Bronchoconstrictor
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Acetazolamide Diuretic Carbonic anhydrase inhibitor
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Alendronate Anti-osteoporesis Bisphosphonate Inhibitor of osteoclast-mediated bone resorption
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Amikacin Aminoglycoside antibiotic Bactericidal protein synthesis inhibitor 30S ribosome Freezes initiation
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Amiloride Potassium sparing diuretic Sodium channel inhibitor Antihypertensive
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Aminoglycosides Antibiotics Bactericidal protein synthesis inhibitors 30S ribosome Freeze initiation
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Amlodipine Antihypertensive Calcium channel blocker
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Amoxicillin Penicillin antibiotic Cell wall synthesis inhibitor Antiulcer Amino penicillin Inhibits peptidoglycan cross-linking
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Ampicillin Penicillin antibiotic Cell wall synthesis inhibitor Amino penicillin Inhibits peptidoglycan cross-linking
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Atenolol Sympatholytic 1 adrenergic antagonist Antihypertensive Antiarrhythmic Antianginal Bronchoconstrictor
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Azithromycin Macrolide antibiotic Bacteriostatic protein synthesis inhibitor 50S ribosome Inhibits translocation
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Aztreonam New lactam antibiotic Monobactam
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Bacitracin Antibiotic Cell wall synthesis inhibitor Topical, not a lactam, Inhibits dephosphorylation of bactoprenol
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Benazopril Antihypertensive Converting enzyme inhibitor
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Benzathine penicillin G Penicillin antibiotic Cell wall synthesis inhibitor Inhibits peptidoglycan cross-linking Repository preparation
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Betaxolol Sympatholytic 1 adrenergic antagonist Antihypertensive Glaucoma medication Bronchoconstrictor
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Bretylium Sympatholytic Class III antiarrhythmic K + channel blocker
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Bumetanide Loop diuretic Na + -K + -2Cl - transporter inhibitor
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Captopril Antihypertensive Converting enzyme inhibitor Heart failure treatment Angioedema producer
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Carbenicillin Penicillin antibiotic Cell wall synthesis inhibitor Anti-pseudomonal penicillin Inhibits peptidoglycan cross-linking
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Carteolol Sympatholytic adrenergic antagonist Antihypertensive Bronchoconstrictor
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Cefaclor Cephalosporin antibiotic Cell wall synthesis inhibitor 2 nd generation Oral
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Cefadroxil Cephalosporin antibiotic Cell wall synthesis inhibitor 1 st generation Oral
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Cefepime Cephalosporin antibiotic Cell wall synthesis inhibitor 4 th generation CSF penetration
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Cefotaxime Cephalosporin antibiotic Cell wall synthesis inhibitor 3 rd generation CSF penetration
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Cefoxitin Cephalosporin antibiotic Cell wall synthesis inhibitor 2 nd generation
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Ceftazidime Cephalosporin antibiotic Cell wall synthesis inhibitor 3 rd generation
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Ceftriaxone Cephalosporin antibiotic Cell wall synthesis inhibitor 3 rd generation CSF penetration
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Cefuroxime Cephalosporin antibiotic Cell wall synthesis inhibitor 2 nd generation CSF penetration
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Cephalexin Cephalosporin antibiotic Cell wall synthesis inhibitor 1 st generation Oral
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Cephalosporins Antibiotics lactam Cell wall synthesis inhibitors Inhibit cross-linking of peptidoglycan
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Cephalothin Cephalosporin antibiotic Cell wall synthesis inhibitor 1 st generation Oral
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Chloramphenicol Antibiotic Bacteriostatic protein synthesis inhibitor 50S ribosome Inhibits peptide bond formation
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Chlorthalidone Thiazide-like diuretic Na-Cl symporter inhibitor Antihypertensive
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Chlorothiazide Thiazide diuretic Na-Cl symporter inhibitor
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Ciprofloxacin Fluoroquinolone antibiotic DNA replication inhibitor Inhibits bacterial DNA gyrase
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Clarithromycin Macrolide antibiotic Bacteriostatic protein synthesis inhibitor Antiulcer 50S ribosome Inhibits translocation
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Clavulanic acid -lactamase inhibitor Combined with antibacterials
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Clindamycin Antibiotic Bacteriostatic protein synthesis inhibitor 50S ribosome Anaerobic infections
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Clonidine Sympatholytic 2 adrenergic agonist Antihypertensive
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Cloxacillin Penicillin antibiotic Cell wall synthesis inhibitor Penicillinase resistant penicillin Inhibits peptidoglycan cross-linking
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Cycloserine Antibiotic Cell wall synthesis inhibitor Secondary TB drug Inhibits formation of Park nucleotide
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Dapsone Sulfone antibiotic Nucleic acid and protein synthesis inhibitor Inhibits dihydropteroate synthetase Leprosy
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Desmopressin acetate Synthetic analogue of arginine vasopressin Used in treatment of bleeding disorders
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Diazoxide Vasodilator Antihypertensive
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Diltiazem Class IV antiarrhythmic Antihypertensive Ca 2+ channel blocker
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Doxazosin Sympatholytic 1 adrenergic antagonist Antihypertensive
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Doxycycline Tetracycline antibiotic Bacteriostatic protein synthesis inhibitor 30S ribosome Prevents aminoacyl tRNA attachment
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Enalapril Antihypertensive Converting enzyme inhibitor Angioedema producer
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Eplerenone Aldosterone receptor antagonist
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Eprosartan Antihypertensive Angiotensin receptor blocker (ARB)
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Erythromycin Macrolide antibiotic Bacteriostatic protein synthesis inhibitor 50S ribosome Inhibits translocation
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Esmolol Sympatholytic 1 adrenergic antagonist Class II Antiarrhythmic Antihypertensive Bronchoconstrictor
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Ethacrynic acid Loop diuretic Na-K-2Cl symporter inhibitor
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Etidronate Anti-osteoporesis Bisphosphonate Inhibitor of osteoclast-mediated bone resorption
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Felodipine Antihypertensive Calcium channel blocker
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Fluorinated Quinolones ciprofloxacin, norfloxacin Antibiotics DNA replication inhibitors Inhibit bacterial DNA gyrase
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Fosinopril Antihypertensive Converting enzyme inhibitor
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Furosemide Loop diuretic Na-K-2Cl symporter inhibitor Antihypertensive
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Gentamicin Aminoglycoside antibiotic Bactericidal protein synthesis inhibitor 30S ribosome Freezes initiation
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Guanabenz Sympatholytic Antihypertensive
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Guanadrel Sympatholytic Antihypertensive
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Guanethidine Sympatholytic Antihypertensive
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Guanfacine Sympatholytic 2 adrenergic agonist Antihypertensive
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Hydralazine Vasodilator Antihypertensive
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Hydrochlorothiazide Thiazide diuretic Na-Cl symporter inhibitor Antihypertensive
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Imipenem/Cilastatin New lactam antibiotic Cilastatin inhibits a kidney dipeptidase that inactivates imipenem
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Indapamide Thiazide-like diuretic Na-Cl symporter inhibitor Antihypertensive
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Irbesartan Antihypertensive Angiotensin receptor blocker (ARB)
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Isradipine Antihypertensive Calcium channel blocker
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Labetalol Sympatholytic and adrenergic antagonist Antihypertensive
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Linezolid Oxazolidinone antibiotic Protein synthesis inhibitor 50S ribosomal subunit
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Losartan Antihypertensive Angiotensin receptor blocker (ARB)
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Lypressin Antidiuretic hormone analogue
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Macrolides erythromycin, azithromycin, clarithromycin Antibiotics Bacteriostatic protein synthesis inhibitors 50S ribosome
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Mannitol Osmotic diuretic
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Methenamine Urinary tract antiseptic Decomposes to formaldehyde in acidic environment
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Methicillin Penicillin antibiotic Cell wall synthesis inhibitor Pencillinase resistant penicillin Inhibits peptidoglycan cross-linking
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Methydopa Sympatholytic 2 adrenergic agonist Antihypertensive
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Metolazone Thiazide-like diuretic Na-Cl symporter inhibitor Antihypertensive
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Metoprolol Sympatholytic 1 adrenergic antagonist Antihypertensive Heart failure medication Bronchoconstrictor
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Metronidazole Antibiotic Antiparasitic Antiulcer Anaerobes Reduction leads to intermediates that damage DNA
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Minocycline Tetracycline antibiotic Bacteriostatic protein synthesis inhibitor 30S ribosome Prevents aminoacyl tRNA attachment
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Minoxidil Vasodilator Antihypertensive
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Nadolol Sympatholytic adrenergic antagonist Antihypertensive
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Nafcillin Penicillin antibiotic Cell wall synthesis inhibitor Penicillinase resistant penicillin Inhibits peptidoglycan cross-linking
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Nalidixic acid Urinary tract antiseptic Quinolone Inhibits bacterial DNA gyrase
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Neomycin Aminoglycoside antibiotic Bactericidal protein synthesis inhibitor 30S ribosome Freezes initiation Topical
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Netilmicin Aminoglycoside antibiotic Bactericidal protein synthesis inhibitor 30S ribosome Freezes initiation
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Nicardipine Antihypertensive Calcium channel blocker
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Nifedipine Antihypertensive Antianginal Calcium channel blocker
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Nisoldipine Antihypertensive Calcium channel blocker
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Nitrendipine Antihypertensive Calcium channel blocker
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Nitrofurantoin Urinary tract antiseptic Reduction leads to intermediates that damage DNA
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Nitroglycerine Venodilator Antianginal
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Nitroprusside Vasodilator Antihypertensive
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Norfloxacin Fluoroquinolone antibiotic DNA replication inhibitor Inhibits bacterial DNA gyrase
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Oxacillin Penicillin antibiotic Cell wall synthesis inhibitor Pencillinase resistant penicillin Inhibits peptidoglycan cross-linking
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Oxytetracycline Tetracycline antibiotic Bacteriostatic protein synthesis inhibitor 30S ribosome Prevents aminoacyl tRNA attachment
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Pamidronate Anti-osteoporesis Bisphosphonate Inhibitor of osteoclast-mediated bone resorption
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Para-aminosalicylic acid Antibiotic Nucleic acid and protein synthesis inhibitor Inhibits dihydropteroate synthetase Secondary TB drug
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Penbutolol Sympatholytic adrenergic antagonist Antihypertensive Bronchoconstrictor
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Penicillins lactam antibiotics Cell wall synthesis inhibitors Inhibit cross-linking of peptidoglycan
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Penicillin G Penicillin antibiotic Cell wall synthesis inhibitor Acid labile Inhibits peptidoglycan cross-linking
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Penicillin V Penicillin antibiotic Cell wall synthesis inhibitor More acid resistant than Penicillin G Inhibits peptidoglycan cross-linking
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Phenoxybenzamine Sympatholytic adrenergic antagonist Antihypertensive
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Phentolamine Sympatholytic adrenergic antagonist Antihypertensive
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Pindolol Sympatholytic adrenergic antagonist Antihypertensive Bronchoconstrictor
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Piperacillin Penicillin antibiotic Cell wall synthesis inhibitor Anti-pseudomonal penicillin Inhibits peptidoglycan cross-linking
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Polymyxin B Antibiotic Disrupts gram negative cell membrane Binds phosphatidylethanolamine Bactericidal
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Prazosin Sympatholytic 1 adrenergic antagonist Antihypertensive
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Probenecid Uricosuric Adjunct in penicillin therapy
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Procaine Penicillin G Penicillin antibiotic Cell wall synthesis inhibitor Repository preparation Inhibits peptidoglycan cross-linking
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Propranolol Sympatholytic adrenergic antagonist Class II antiarrhythmic Antihypertensive Bronchoconstrictor
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Quinapril Antihypertensive Converting enzyme inhibitor
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Quinethazone Thiazide-like diuretic Na-Cl symporter inhibitor
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Quinopristin/Dalfopristin Streptogramin antibiotic Protein synthesis inhibitor 50S ribosomal subunit
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Ramipril Antihypertensive Converting enzyme inhibitor
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Reserpine Sympatholytic Antihypertensive
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Rifampin Antibiotic Nucleic acid synthesis inhibitor Inhibits DNA dependent RNA polymerase Major drug for TB
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Silver sulfadiazine Sulfonamide antibiotic Microbial nucleic acid and protein synthesis inhibitor Inhibits dihydropteroate synthetase Topical
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Spectinomycin Antibiotic Bacteriostatic protein synthesis inhibitor 30S ribosome
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Spironolactone Potassium sparing diuretic Antiandrogen Aldosterone receptor antagonist Androgen receptor antagonist Testosterone synthesis inhibitor Antihypertensive Heart failure treatment
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Streptomycin Aminoglycoside antibiotic Bactericidal protein synthesis inhibitor 30S ribosome Freezes initiation
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Sulfacetamide Sulfonamide antibiotic Microbial nucleic acid and protein synthesis inhibitor Inhibits dihydropteroate synthetase Topical
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Sulfadoxine Sulfonamide antibiotic Microbial nucleic acid and protein synthesis inhibitor Dihydropteroate synthetase inhibitor
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Sulfamethoxazole Sulfonamide antibiotic Microbial nucleic acid and protein synthesis inhibitor Inhibits dihydropteroate synthetase
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Sulfisoxazole Sulfonamide antibiotic Nucleic acid and protein synthesis inhibitor Inhibits dihydropteroate synthetase
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Sulfonamides Antibiotics Nucleic acid and protein synthesis inhibitors Inhibit dihydropteroate synthetase
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Telmisartan Antihypertensive Angiotensin receptor blocker (ARB)
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Terazosin Sympatholytic 1 adrenergic antagonist Antihypertensive Treatment for benign prostatic hypertrophy
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Tetracycline Antibiotic Bacteriostatic protein synthesis inhibitor Antiulcer 30S ribosome Prevents aminoacyl tRNA attachment
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Ticarcillin Penicillin antibiotic Cell wall synthesis inhibitor Anti-pseudomonal penicillin Inhibits peptidoglycan cross-linking
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Timolol Sympatholytic adrenergic antagonist Antihypertensive Glaucoma treatment Anti-anginal Bronchoconstrictor
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Tobramycin Aminoglycoside antibiotic Bactericidal protein synthesis inhibitor 30S ribosome Freezes initiation
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Tosemide Loop diuretic Na-K-2Cl symporter inhibitor
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Triamterene Potassium sparing diuretic Sodium channel inhibitor Antihypertensive
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Trimethaphan Sympatholytic Anticholinergic Nicotinic antagonist Antihypertensive
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Trimethoprim Antibiotic Protein and nucleic acid synthesis inhibitor Inhibits bacterial dihydrofolate reductase
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Valsartan Antihypertensive Angiotensin receptor blocker (ARB)
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Vancomycin Antibiotic Inhibits cell wall synthesis Not a lactam
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Arginine vasopressin (Antidiuretic hormone; ADH) Hypothalamic (posterior pituitary) hormone Antidiuretic Vasoconstrictor
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Verapamil Class IV antiarrhythmic Antihypertensive L-type Ca 2+ channel blocker Antianginal
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