1. Essentials of Human Anatomy & Physiology Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings Seventh Edition Elaine N. Marieb Chapter 8 The Muscular System

2. Function of Muscles Slide 6.8 Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings  Produce movement of the body and its parts  Maintain posture  Stabilize joints  Generate and distribute heat  Provides muscle tone  Propel body fluids and food

3. The Muscular System Slide 6.1 Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings  Muscles are responsible for all types of body movement – they contract or shorten and are the machine of the body  Three basic muscle types are found in the body  Skeletal muscle  Cardiac muscle  Smooth muscle

4. Characteristics of Muscles Slide 6.2 Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings  Muscle cells are elongated (muscle cell = muscle fiber)  Contraction of muscles is due to the movement of microfilaments

5. Skeletal Muscle Characteristics Slide 6.3 Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings  Most are attached by tendons to bones  Cells are multinucleate  Striated – have visible banding  Voluntary – subject to conscious control

6. Smooth Muscle Characteristics Slide 6.6 Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings  Has no striations  Spindle-shaped cells  Single nucleus  Involuntary – no conscious control  Found mainly in the walls of hollow organs  Slow, sustained and tireless Figure 6.2a

7. Cardiac Muscle Characteristics Slide 6.7 Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings  Has striations  Usually has a single nucleus  Joined to another muscle cell at an intercalated disc  Involuntary  Found only in the heart  Steady pace! Figure 6.2b

8. Microscopic Anatomy of Skeletal Muscle Slide 6.9a Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings  Cells are multinucleate Figure 6.3a

9. Microscopic Anatomy of Skeletal Muscle Slide 6.10a Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings  Myofibril  Bundles of myofilaments  Myofibrils are aligned to give distrinct bands  I band = light band  A band = dark band Figure 6.3b

10. Microscopic Anatomy of Skeletal Muscle Slide 6.10b Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings  Sarcomere  Contractile unit of a muscle fiber Figure 6.3b

11. Microscopic Anatomy of Skeletal Muscle Slide 6.11a Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings  Organization of the sarcomere  Thick filaments = myosin filaments  Composed of the protein myosin  Has ATPase enzymes Figure 6.3c

12. Microscopic Anatomy of Skeletal Muscle Slide 6.12a Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings  Myosin filaments have heads (extensions, or cross bridges)  Myosin and actin overlap somewhat Figure 6.3d

13. Properties of Skeletal Muscle Activity (single cells or fibers) Slide 6.13 Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings  Irritability – ability to receive and respond to a stimulus  Contractility – ability to shorten when an adequate stimulus is received

14. Nerve Stimulus to Muscles Slide 6.14 Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings  Skeletal muscles must be stimulated by a nerve to contract (motor neuron)  Motor unit  One neuron  Muscle cells stimulated by that neuron Figure 6.4a

15. The Sliding Filament Theory of Muscle Contraction Slide 6.17a Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings  Activation by nerve causes myosin heads (crossbridges) to attach to binding sites on the thin filament  Myosin heads then bind to the next site of the thin filament Figure 6.7

16. The Sliding Filament Theory of Muscle Contraction Slide 6.17b Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings  This continued action causes a sliding of the myosin along the actin  The result is that the muscle is shortened (contracted) Figure 6.7

17. The Sliding Filament Theory Slide 6.18 Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings Figure 6.8

18. Contraction of a Skeletal Muscle Slide 6.19 Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings  Muscle fiber contraction is “all or none”  Within a skeletal muscle, not all fibers may be stimulated during the same interval  Different combinations of muscle fiber contractions may give differing responses  Graded responses – different degrees of skeletal muscle shortening, rapid stimulus = constant contraction or tetanus

19. Muscle Response to Strong Stimuli Slide 6.22 Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings  Muscle force depends upon the number of fibers stimulated  More fibers contracting results in greater muscle tension  Muscles can continue to contract unless they run out of energy

20. Energy for Muscle Contraction Slide 6.23 Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings  Initially, muscles used stored ATP for energy  Bonds of ATP are broken to release energy  Only 4-6 seconds worth of ATP is stored by muscles  After this initial time, other pathways must be utilized to produce ATP

21. Muscle Fatigue and Oxygen Debt Slide 6.27 Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings  When a muscle is fatigued, it is unable to contract  The common reason for muscle fatigue is oxygen debt  Oxygen must be “repaid” to tissue to remove oxygen debt  Oxygen is required to get rid of accumulated lactic acid  Increasing acidity (from lactic acid) and lack of ATP causes the muscle to contract less

22. Types of Muscle Contractions Slide 6.28 Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings  Isotonic (aka aerobic or dynamic) contractions  Myofilaments are able to slide past each other during contractions  The muscle shortens  Isometric (resistance contractions)  Tension in the muscles increases  The muscle is unable to shorten

23. Muscle Tone Slide 6.29 Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings  A continuous contraction of fibers which keeps muscles shapely & healthy  Some fibers are contracted even in a relaxed muscle  Different fibers contract at different times to provide muscle tone  The process of stimulating various fibers is under involuntary control

24. Muscles and Body Movements Slide 6.30a Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings  Movement is attained due to a muscle moving an attached bone Figure 6.12

25. Muscles and Body Movements Slide 6.30b Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings  Muscles are attached to at least two points  Origin – attachment to an immoveable bone  Insertion – attachment to a movable bone Figure 6.12

26. Effects of Exercise on Muscle Slide 6.31 Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings  Results of increased muscle use  Increase in muscle size  Increase in muscle strength  Increase in muscle efficiency  Muscle becomes more fatigue resistant

27. Types of Ordinary Body Movements Slide 6.32 Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings  Flexion – decreases angle of joint and brings two bones closer together  Extension- opposite of flexion  Rotation- movement of a bone in longitudinal axis, shaking head “no”  Abduction/Adduction (see slides)  Circumduction (see slides)

28. Body Movements Slide 6.33 Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings Figure 6.13

29. Left: Abduction – moving the leg away from the midline Above – Adduction- moving toward the midline Right: Circumduction: cone- shaped movement, proximal end doesn’t move, while distal end moves in a circle.

30. Types of Muscles Slide 6.35 Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings  Prime mover – muscle with the major responsibility for a certain movement  Antagonist – muscle that opposes or reverses a prime mover  Synergist – muscle that aids a prime mover in a movement and helps prevent rotation  Fixator – acts to hold a bone still (origin) so that all tension can be used to move insertion bone

31. Naming of Skeletal Muscles Slide 6.36a Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings  Direction of muscle fibers  Example: rectus (straight)  Relative size of the muscle  Example: maximus (largest)

32. Naming of Skeletal Muscles Slide 6.36b Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings  Location of the muscle  Example: many muscles are named for bones (e.g., temporalis)  Number of origins  Example: triceps (three heads)

33. Naming of Skeletal Muscles Slide 6.37 Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings  Location of the muscles origin and insertion  Example: sterno (on the sternum)  Shape of the muscle  Example: deltoid (triangular)  Action of the muscle  Example: flexor and extensor (flexes or extends a bone)

34. Head and Neck Muscles Slide 6.38 Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings Figure 6.14

35. Trunk Muscles Slide 6.39 Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings Figure 6.15

36. Deep Trunk and Arm Muscles Slide 6.40 Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings Figure 6.16

37. Muscles of the Pelvis, Hip, and Thigh Slide 6.41 Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings Figure 6.18c

38. Muscles of the Lower Leg Slide 6.42 Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings Figure 6.19

39. Superficial Muscles: Anterior Slide 6.43 Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings Figure 6.20

40. Superficial Muscles: Posterior Slide 6.44 Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings Figure 6.21

41. Disorders relating to the Muscular System Muscular Dystrophy: inherited, muscle enlarge due to increased fat and connective tissue, but fibers degenerate and atrophy