1. Taiwan Tuberculosis Symposium Nov.30-Dec.1, 2005 Taipei International Convention Center

2. Welcome Address Dear Colleagues, We warmly welcome you to the Taiwan Tuberculosis Symposium. We are all gathered here to address new scientific data and research results on the tuberculosis control and also aim to increase the public awareness. The topics in this symposium include: tuberculosis epidemiology, laboratory diagnosis, nosocomial infection control and stigma and solution of tuberculosis infection in aboriginal areas in Taiwan. Tuberculosis causes 2 million deaths and unquantifiable suffering each year, despite the fact that proven, cost-effective treatments have been available for decades. Over 10 years ago, the World Health Organization (WHO) declared TB a global health emergency. It is still an emergency today. Tuberculosis, the statutory infectious disease with most cases in Taiwan, not only threatens people's health but influences our national image and competitiveness. Besides, due to flourishing tourism and frequent international dealings, epidemic prevention and control become a real challenge. An important issue on the research of tuberculosis, with all the blessings and efforts, actively break through the bottleneck and improve the public health. Sharing information and experiences with colleagues will enable us to learn from one another, strengthen cooperation, promote research and move forward to control of tuberculosis in Taiwan.

3. November 30, 2005, Wednesday Site ： TICC Rm. 101AB (1F) 08:30~09:00 ： Registration 09:00~09:10 ： Opening Remark Dr.Tzay-Jinn Chen, Deputy Minister, Department of Health, Executive Yuan, Taiwan 09:10~12:00 ： Session I ： TB Epidemiology and ControlModerator Dr. Steve Hsu-Sung Kuo, Director-general, Taiwan CDC Prof. Ruey-Shiung Lin, National Taiwan University College of Medicine, Taiwan 09:10~09:30 SI-1 TB Epidemiology and Control in Taiwan Dr. Yi-Chun Wu, Center for Disease Control, Taiwan 09:30~09:50 SI-2 TB Epidemiology and Control in the United States Dr. Kashef Ijaz, Center for Disease Control, U.S.A. 09:50~10:10 SI-3 National TB Program Review Dr. Chen-Yuan Chiang, International Union Against Tuberculosis and Lung Disease 10:10~10:40 ： Discussion Program November 30, 2005

4. 11:00~11:20 SI-4 Factors Affecting the Successful Treatment for Tuberculosis Patients in Taiwan Assistant Prof. Pei-Tseng Kung, Asia University, Taiwan 11:20~11:40 SI-5 Sociocultural Aspects of Tuberculosis: a Case Study of Immigrant Tuberculosis Assistant Prof. Ming-Jung Ho, National Taiwan University College of Medicine 11:40~12:00 ： Discussion Program November 30, 2005

5. 13:30~17:30 ： Session II ： TB Laboratory Diagnosis Moderator Prof. Ih-Jen Su, National Health Research Institute, Taiwan Mr. Wen-Yi Shih, Deputy Director-general, Taiwan CDC 13:30~14:00 SII-1 Molecular Epidemiology of Mycobacterium tuberculosis Strains in Taiwan Dr. Ruwen Jou, Center for Disease Control, Taiwan 14:00~14:30 SII-2 DNA typing of Mycobacterium tuberculosis isolates for epidemiological research Dr. Dick van Soolingen, National Institute for Public Health and Environment, The Netherlands 14:30~15:00 SII-3 The Quality Status of the MTB Laboratories in Taiwan. M.S. Tsu-Lan Wu, Chang-Gung Memorial Hospital, Taiwan 15:00~15:30Discussion Program November 30, 2005

6. 15:50~16:30 The Role of γ- Interferon for TB Early Diagnosis 15:50~16:10 Can Whole Blood Interferon-Gamma Tests Replace Tuberculin Skin Test as a Diagnostic Tool for Mycobacterium tuberculosis Infection? Dr. Yung-Ching Liu, Kaohsiung Veterans General Hospital, Taiwan 16:10~16:30 Compare Two Step Tuberculin skin Test and Quantiferon-TB Gold Test in the Elderly and HCWs of Taiwan Dr. Gwan-Han Shen, Taichung Veterans General Hospital, Taiwan 16:30~17:00 Recent Advances in Mycobacterial Genomics Dr. Wei-Juin Su, Taipei City Hospital, Taiwan 17:00~17:30Discussion 18:00 Welcoming Reception Program November 30, 2005

7. December 1, 2005, Thursday Site ： TICC Rm. 101AB (1F) 08:45~12:20 Session III TB Clinical Diagnosis and Nosocomial Infection ControlModerator Prof. Pan-Chyr Yang, National Taiwan University College of Medicine （ and Hospital ） Prof. Shan-Chwen Chang, National Taiwan University College of Medicine （ and Hospital ） Prof. Kwen-Tay Luh, National Taiwan University College of Medicine, Taiwan 08:45~09:15 SIII-1 TB outbreak in Taiwan Yung-Ming Chang, Section Chief, Center for Disease Control, Taiwan 09:15~09:45 SIII-2 Tuberculosis Outbreak Investigations Dr. John Oeltmann, Center for Disease Control, U.S.A. 09:45~10:15 SIII-3 TB Transmission and Control in Congregate Settings:Source,Organism,and Environmental Factors Dr. Edward Nardell, Harvard Medical School,U.S.A. 10:15~10:45Discussion Program December 1, 2005

8. 11:00~11:30 SIII-4 Factors Changing the Manifestation of Pulmonary Tuberculosis Dr. Jann-Yuan Wang, Department of Internal Medicine, National Taiwan University Hospital, Yun-Lin Branch, Taiwan 11:00~11:30 SIII-5 Factors Changing the Manifestation of Pulmonary Tuberculosis Dr. Jann-Yuan Wang, Department of Internal Medicine, National Taiwan University Hospital, Yun-Lin Branch, Taiwan 11:30~12:00 SIII-6 Evaluating the Accuracy of Tuberculosis-Related Cause-of-Death Statements Dr. Tsung-Hsueh Lu, National Cheng Kung University 12:00~12:20Discussion Program December 1, 2005

9. 13:30~17:20 Session IV ： TB in Mountain Area & Aboriginal Groups Prof. Suo-Jen, National Tuberculosis Association, Taiwan Lin-Ting, Deputy Director-general, Taiwan CDC 13:30~14:00 SIV-1 TB Epidemiology in Mountain Area & Aboriginal Groups—Taiwan Experience Ms. Kwei-Feng Wang, Section Chief, Center for Disease Control, Taiwan 14:00~14:30 SIV-2 Molecular Epidemiology of TB Transmission Dynamics in an Aboriginal Township Dr. Ruwen Jou, Center for Disease Control, Taiwan 14:30~15:00 SIV-3 Association of NRAMP 1 Gene Polymorphisms with Susceptibility to Tuberculosis in Taiwanese Aboriginals Dr.Ih-Jen Su, National Health Research Institutes, Taiwan 15:00~15:30 Discussion Program December 1, 2005

10. 15:50~16:20 SIV-4 DOTS Study in Hualien County-Preliminary Report Dr. Jen-Jyh Lee, Tzu Chi Buddhist General Hospital 16:20~16:50 SIV-5 Stigma & Solution of TB Infection in Taiwan Aboriginal Society Dr. Chi-Wen Kung, Hualien Chi-An Health Station, Taiwan 16:50~17:20 Discussion 17:20~ Close of Meeting Program December 1, 2005

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