2.  Tablets for suspension  Percentage preparations  Aliquots  Alligation  Solubility  Specific gravity  Capsule packing Will go over in PPC

3.  Tsp = 5 mL  Tbsp = 15 ml  1 fl oz ~ 30 mL  1 pint = 473 mL  1 oz = 28.4 g  1 lb = 454 g  1 grain ~65 mg  % (w/v) = g/100 mL  % (v/v) = mL/100 mL  % (w/w) = g/100 g

4.  Patient needs a lisinopril suspension at 15mg/5ml. He will be taking 5ml po daily. How many lisinopril tablets will be needed to make 30 days worth?  What strength tablets will you need?  15mg/5ml for 30 days = 450mg/150ml  Can use 11- 40mg tabs + 1- 10mg tab

5.  Prescription is written for levothyroxine 0.1mg/mL; dispense 60 mL.  We have 25mcg tabs of levothyroxine available  How many tablets will we need to use?  60mL x 0.1mg/mL = 6 mg of levo  6mg levo x (1 tab/0.025mg levo) = 240 tabs

6.  What if you need a partial tablet?  Example: Compounding formula calls for 4.8 tablets of ABC. How do we get this?  Weigh out 5 tablets (example = 1.255 g)  Create proportion equation  1.255 g = x g 5 tabs 4.8 tab  x = 1.2048 g needed

7.  Prescription is written for 1 lb cream (454g) with urea 10% and hydrocortisone 2%.  How much urea and hydrocortisone is in the cream in grams?  Urea: 45.4g; hydrocortisone: 9.08g  How much cream will you need?  454 – (45.4+9.08) = amount of cream = 399.52g

8.  How many mL of hydrocortisone liquid (40mg/mL) will be needed to prepare 30 grams of a 0.25% cream (w/w)?  0.25g/100g x 30g = 0.075g HC needed  75mg HC x (1mL/40mg) = 1.875mL liquid needed

9.  What if what you need to weigh is <120mg?  Example: Rx calls for 7.5mg of ABC in preparation. How do we measure this?  Min weighable qty on our balance: 120mg  To make it easier, most pharmacies do aliquots in % (ie. 1%, 10%)  In this case, to make aliquot we can make a 1g/100g mixture to equal ABC 1% ▪ How much do you need to weigh of ABC 1% to equal 7.5mg? ▪ 750mg (check  750mg x 0.01 = 7.5mg)

10.  Complete name of drug/source used  Name of manufacturer  Lot number of drug source  Expiration date of source  Amounts of materials used  Total amount at top of table  Information placed on back of the rx or in a log book

11.  T-Bar  Line between numbers represent decimal place  Pharmacy compounding log or worksheet  Always include units! (mL, g, etc.)  When calculating, do not round until making a measurement 30 mL Ingredient 1 0 (lot #AB123, exp 1/16) Ingredient 2 2 (lot #CD435, exp 3/15) Ingredient 3 QS 30 (lot #9780DN, exp 5/18) 425 g 230 g mL