1. Figure 1 A B 4µM8µM16µM32µM 0 NS ** *** Infected and 4 µ M STS treated Infected and 32 µM STS treated Mock Infected and 4 µM STS treated Mock Infected and 32 µ M STS treated Cleaved PARP Full-length PARP

2. Figure 2 Infected Mock infected Caspase 3 Cleaved Caspase 3 B C A Caspase 9 Cleaved Caspase 9 Infected Mock infected D ***

3. Fig 3 DetachedAttached Mock Infected STS Treated CCHFV Infected Mock treated CCHFV Infected STS Treated abcd A B Attached Cells Detached Cells ***

4. Activated caspase 3 (fluorescence unit) * Fig 4 flag-Bax 0 0 0.3 0.3 0.3 0.3 myc-N 0 1.5 1.5 1.0 0 A * B anti-PARP anti-flag anti-myc anti-actin

5. Fig 5 Full-length Bid Truncated Bid Mock-Infected 24hr.p.i 48 hr.p.i 24hr.p.i 48 hr.p.i Mock-Infected Infected Detached cellsAttached cells

6. bca 24 487248724872 Full-length PARP Cleaved PARP Fig 6 A B ****** C