1. CLINICAL CHEMISTRY Introduction to basic clinical chemistry BY BRUCE MUTUA

2. Trends and developments Reagents Powders(lyophilised) Wet Dry Equipments Colorimeters Semi-automation Benchtop automation Stand alone automation Page 2

3. Clinical Chemistry Instruments and Reagents Market Factors influencing the trends and development TAT lab size Governmental QM regulation: registration, accreditation, validation Cost factors Instrument financing options sought by healthcare authorities Reagent rental/refurbished instruments competition Page 3

4. Clinical Chemistry Instruments and Reagents Market What do customers expect in this market? Page 4 Ease of Use Reliability Appropriate Workload Random Access Walk Away Capability Connectivity to LIS Service and Support “The 7 Mantras of Automation“

5. Page 5 CHEM-LABS SOLUTIONS Manual / Semi- automatic Low Throughput Automation Medium Throughput Automation High Throughput Automation Very high Throughput Automation Mega-high Throughput Automation

6. HumaStar 600 Answers to RTAT and quality results Offering unique solutions Provides attractive conditions High value to customers

7. HumaStar 600 FEATURES software version 1.8.0 super design functionality performance-optimizing hardware Page 7

8. DESIGN-UNIQUE Super design with improved ergonomics: Instrument lid for full optical access Rotor covers asymmetrical Page 8

9. System reagents Inflammatory and rheumatoid tests Lipoproteins Plasma proteins Electrolytes Substrates enzymes

10. Consumables: Diluent Cuvettes clean Tip Cleaning kit Wash additive

11. CONT: Analysis modes: -Random access (Continuous Sample Loading) Sample Volume: -2-100µL

12. Sample Tray: Samples has 19 positions for continuous loading Sample can hold: -Micro cups ( 0.5ml) -Standard Cups (1.5ml) -Primary tubes (5ml.7ml,10ml)

13. Reaction: Water consumption of 4 l/hour Warm air incubation at 37°C Reaction time of 12 min. Reaction cuvettes are re-usable with 6mm thickness

14. Reagents: HumaStar 600 has refrigerated reagent tray holding up to 48 different positions. HumaStar 600 has a cooled reagent tray where 30ml & 70ml can be placed. The reagent tray includes an integrated barcode reader for 24 inner & 24 outer positions. Diluents as well as buffer solutions are also placed in the reagent tray. Bar coder Technology is used at the reagent & Sample sector Positions.

15. Cuvettes: Samples & Reagents are dispensed into a multiple cuvettes strip. Reaction trays hold 160 Cuvettes in two separate reaction Trays.

16. HumaStar 600 Method calibration – a calibration can be re-used Software 1.8.0 Page 16

17. HumaStar 600 Intensive cuvette cleaning feature at day´s end Software 1.8.0 Page 17

18. HumaStar 600 Software 1.8.0 –QC statistics automatically shows the current day –The QC result plot shows the mean –Additional reports integrated –For samples birth date or age can be used –Patient names can be modified –And much more… Page 18

19. HumaStar 600 Controlled evaporation protection – covers also for small openings Sample tray access enlarged Page 19

20. HumaStar 600 Hardware Improvement Clot detection as combined hardware/software update: Control electronics completely re-designed Reduced operating noise Page 20

21. lower western CASE STUDY 1.COLORIMETERS-15% 2.SEMI AUTOMATION-60% 3.BENCHTOP AUTOMATION-10% 4.STAND ALONE AUTOMATION-0.0% 5.NO EQUIPMENT-15%

22. CHEM-LABS OFFER @ lower western ON 26/08/2011 1.SYSTEM BUSINESS 2.UPGRADES/TRADE IN 3.SPECIAL PRICES DURING THE CONFERENCE Page 22

23. HumaStar 600 Summary Chem-labs delivers the right tools for continued success Our commitment is demonstrated by product improvements Your chance to improve quality in lab results

24. GO FOR THE KILL