1. Group 3 Our Objective: We made a molecule to disrupt marijuana's effects.And try to cure a person with severe addiction to this drug.

2. We have to learn, what marijuana is about Before talking about our project

3. Marijuana is a green, brown or gray mixture of dried shredded leaves, stems, seeds and flowers from the hemp plant (or Cannabis sativa). The main active chemical in marijuana is THC (delta-9- tetrahydrocannabinol). What is marijuana?

4. 1.Distorted perception (sights, sounds, time, touch) 2.Trouble with thinking and problem solving 3.Loss of motor coordination 4.Increased heart rate 5.Anxiety 6.Dry mouth and throat Short term effects of marijuana

5. 1.Additional stress on the heart, which is a particular concern to users who already suffer from high blood pressure, hardening of the arteries or are prone to strokes. 2.Reproductive system problems. Marijuana suppresses the production of male sex hormones, shrinks the testes, and inhibits sperm production. Marijuana has also been shown to inhibit ovulation in women. 3.Difficulty concentrating and short-term memory loss 4.A weakened immune system. THC has been found to impair the body’s natural disease-fighting abilities, increasing the risk of bacterial infections and tumors. Long term effects of marijuana

6. 1.Insomnia 2.Restlessness 3.Loss of appetite 4.Irritability 5.Intense craving to smoke marijuana again Marijuana users who stop taking the drug have:

10. MOLECULE OF MARIJUANA

11. THC's chemical structure is similar to the brain chemical anandamide. Similarity in structure allows drugs to be recognized by the body and to alter normal brain communication

12. How does the drug alter neurotransmission

13. WE MIX THE WORD PLEASURE WITH THE WORD ANANDAMIDE, FINALLY WE GOT: PLE + MIDE = PLEMIDE The name of the Product

14. OUR MOLECULE

15. Molecular Formula : CH3 C8 OH Molecular Weight : 48.602578 Molecular Name :ZULTRATUM Qualitative Data : Composed of atom(s) of Carbon (C), Hydrogen (H), Oxygen (O) Quantitative Data :Composed of 8 atoms (s) of Carbon, 4 atoms of Hydrogen, an 1 atom of Oxygen Compounds: hydroxide, carbogen, Description

16. The name of the molecule is Zultratum, Zultratum molecule should be soluble in water for better digestion. Once it is inside circulatory system and finally reaches the cell the brain, it should cross the cell membrane of the receptor cell by active transport with the help of a protein. Once inside the cell, Zulltratum shoud stay in the cytoplasm of the receptor cell and block the entry of THC. This molecule finally will cure the addiction. How will reach the brain? and cure the addiction?

17. Plemide How we will sell it?

18. https://www.youtube.com/watch?v=oeF6rFN9org https://www.youtube.com/watch?v=k-2pfwCT7S0 https://www.youtube.com/watch?v=FsJzCdFlpyQ ANIMATIONS

19. BIBLIOGRAPHY http://www.tocris.com/pdfs/pdf_downloads/Cannabinoid_Receptor_Ligands_Review.pdf http://w3.icf.uab.es/ficf/es/bin/view/Cannabis/FarmacologiaBasica#Receptores_cannabinoides http://www.nimh.nih.gov/health/educational-resources/brain-basics/brain-basics.shtml http://www.drugabuse.gov/news-events/nida-notes/2007/10/impacts-drugs-neurotransmission http://www.nlm.nih.gov/medlineplus/marijuana.html http://www.drugabuse.gov/news-events/nida-notes/2007/10/impacts-drugs- neurotransmission