1. 1.Go to wiki page – kkramer.pbwiki.com 2.Click on “Biology” in right sidebar 3.Click on “Chapter 12.ppt” on bottom left of table 4.Click on “open” in window that appears to open the PowerPoint 5.Go to “Slide Show” on top menu bar and click on “view show” to view the Power Point

2. Chapter 12 DNA & RNA

3. Pg 291 & 294 The Components & Structure of DNA –Review Monomer = nucleotides Polymer = DNA –DNA chain Phosphate Sugar Base (4) backbone

4. Pg 291 & 294 The Components & Structure of DNA –Bases 4 kinds –Adenine –Thymine –Cytosine –Guanine 2 types –Purines –Pyrimidines

5. Single Strand of DNA

9. 12.2 DNA Replication Replication  “copy” –Use one side as a template to make a compliment –Helicase “unzips” nucleotide pairs –DNA Polymerase adds nucleotide pairs to make new strand

10. 5 Quick Quiz

11. Activity http://www.pbs.org/wgbh/aso/tryit/dna/

12. DNA double helix Nucleosomes w/ histones Coiled nucleosomes (supercoils) Loops of coiled nucleosomes Coiled loops of coiled nucleosomes Chromosome

13. 12.2 DNA Replication Coiling –DNA in a nucleus = 30ft. fishing line in a pea –Wrap around histones for protection

14. 12.3 RNA & Protein Synthesis DNA code = order of amino acids to make protein DNA code  protein process? –Transcription = transcribe = to write/copy –Translation = translate = convert from one form to another

15. 12.3 RNA & Protein Synthesis RNA –3 types mRNA (messenger) rRNA (ribosomal) tRNA (transfer)

16. 12.3 RNA & Protein Synthesis Transcription –RNA Polymerase “unzips” DNA –Single strand of DNA is read & copied to make RNA –Differences btw DNA & RNA Double vs. single stranded Thymine vs uracil nucleotides –DNA code to start and stop Promoter / terminus AUG / UAA, UAG, UGA

17. 12.3 RNA & Protein Synthesis

18. mRNA –Editing Exons – kept Introns – cut out EIEIE EEE

19. 12.3 RNA & Protein Synthesis Translation –Finished mRNA leaves nucleus –Every 3 bases = codon

20. 12.3 RNA & Protein Synthesis Translation –Each codon codes for one amino acid –tRNA matches codon and brings amino acid w/ it (anticodon) –Amino acids attach forming a protein

24. Activity http://www.pbs.org/wgbh/aso/tryit/dna/