1. Human Genetic Diversity By Nataliya Prokhnevska Stanley David Alexander Reese Ryan Haddock JuneHee Chang

2. Introduction  Phylogenetic trees are a way of organizing data that show evolutionary patterns and relationships www.bio.umass.edu

3. Introduction  Scientists use machines called sequencers to sequence entire genomes from collected tissue samples. They use this data to study human genetics and make phylogenetic trees.  A project called 1000 genomes was started by researchers to establish a phylogenetic tree of the entire human race. African-American populations were understudied, so researchers decided to look into their genome.

4. Data  This is the allele frequencies that were collected from the sequenced genomes of each of the different populations of hunter-gatherers www.sciencedirect.com Lachance et al. 2012

5. Results www.sciencedirect.com

6. Discussion  By finding the differences in the sequenced genomes they were able to produce a phylogenetic tree where the different populations of African hunter-gatherers fit into. www.sciencedirect.com Lachance et al. 2012

7. Conclusion  Phylogenetic trees use genetics in order to map out how populations change over time and how they are related to each other.

8. Sources 1. Joseph Lachance, Benjamin Vernot, Clara C. Elbers, Bart Ferwerda, Alain Froment, Jean-Marie Bodo, Godfrey Lema, Wenqing Fu, Thomas B. Nyambo, Timothy R. Rebbeck, Kun Zhang, Joshua M. Akey, Sarah A. Tishkoff, Evolutionary History and Adaptation from High-Coverage Whole-Genome Sequences of Diverse African Hunter-Gatherers, Cell, Volume 150, Issue 3, 3 August 2012, Pages 457-469 2. Cell Press (2012, July 26). Whole-genome sequencing of African hunter-gatherers reveals human genetic diversity. ScienceDaily. 3. Freeman, Scott. "27." Biological Science. 4th ed. Boston: Benjamin Cummings, 2010. 474-92. Print. 4. "Home | 1000 Genomes." Home | 1000 Genomes. N.p., n.d. Web. 8 Sept. 2012..