1. Emergency Medicine Network –Founded in 1996 –Mission: To advance public health objectives through diverse projects in emergency care, particularly multicenter clinical research –MARC, NEDI, ED-SAFE, other projects –Funding: government (~95%), industry, foundations –511 publications (as of May 2016); all age groups, diverse topics – www.EMNet-USA.org

2. Massachusetts General Hospital Established 1811 Harvard teaching hospital Emergency Department –Level 1 Trauma Center (children & adults) –Level 1 Burn Center –108,000 ED visits / year –Harvard-Affiliated EM Residency (HAEMR) www.emnet-usa.org

3. EMNet Coordinating Center Director: Carlos Camargo, MD, DrPH Associate Director: Ashley Sullivan, MS, MPH Program Coordinator: Erica Ruggles Sr. Investigator: Kohei Hasegawa, MD, MPH Investigators: Krislyn Boggs, MPH Janice Espinola, MPH Kamal Faridi, MPH Research Fellows: Diana Balekian, MD, MPH Tadahiro Goto, MD Biorepository Manager: Courtney Tierney, MPH Sr. Project Coordinators: Catalina Gimenez-Zapiola Daphne Suzin Project Coordinators:Julia ChungloKatie Tedesco David ZhengElie Mitri Students, Residents, and Visiting Researchers www.emnet-usa.org 3

4. EMNet (194 US and 41 International sites = 235 sites) Dec 2015 www.emnet-usa.org

5. EMNet Steering Committee Carlos Camargo, MD, DrPH (chair) – Boston, MA Jeffrey Caterino, MD, MPH – Columbus, OH Sunday Clark, MPH, ScD – New York, NY Robert Freishtat, MD, MPH – Washington, DC Jonathan Mansbach, MD, MPH – Boston, MA Ashley Sullivan, MS, MPH – Boston, MA www.emnet-usa.org

7. EMNet Research Focuses on three areas: 1.Respiratory/allergy emergencies 2.Health policy 3.Other public health www.emnet-usa.org

8. Research - MARC Examples Asthma COPD Bronchiolitis Anaphylaxis –Food allergy –Stinging insect Angioedema Smoking cessation Pneumonia Inappropriate use of antibiotics www.emnet-usa.org

9. Research – Health Policy Examples Childhood Health Insurance Program (CHIP) National ED Safety Study (NEDSS) National ED Inventories (NEDI) –USA, 2001 to present –13 states & Indian Health Service –International (multiple) EM Workforce –Emergency Physicians –PAs and NPs Pediatric emergency care www.emnet-usa.org

10. Research – Other Public Health Examples Mental health –Depression –Acute psychiatric services –Opioid overdose –Suicide prevention (ED-SAFE) Health literacy Diabetes Healthcare-associated infections Large dataset analyses (eg, NHAMCS, NEDS, SEDD/SID, Medicare) www.emnet-usa.org

11. Publications, 1997-2016 (as of May 2, 2016) # of manuscript publications: 511 # of investigators with manuscript publications: 667 # sites with manuscript publications: 167 Top 4 journals: Acad Emerg Med (68), Ann Emerg Med (31), J Allergy Clin Immunol (30), Ann Allergy Asthma Immunol (24) www.emnet-usa.org

12. Education Research Fellowship –Started 1996 … folded into the MGH ED fellowship ~2006 –Dr Camargo serves as faculty on multiple NIH training grants Pre-doctoral Research Fellowship –Started 2002 –Duration: 12 months (June to June) Summer Research Fellowship –Started 1999 –Duration: 8 weeks (June to August) Visiting Researcher www.emnet-usa.org/education.htm

13. Community (examples) ED Alert Network (2001-2002) Annual 5k Run for Asthma (2003-2005) EMNet findER www.emnet-usa.org

14. EMNet findER Developed by EMNet at MGH (www.emnet-usa.org)www.emnet-usa.org Locates closest ERs and provides directions Available for free for both iPhone and Android Pediatric version under development (99 cents) 14

15. Clinical (examples) Asthma Education in the ED (2001) AHRQ-sponsored conference at NY Academy of Medicine National Guidelines –NIH anaphylaxis (2004, 2005) –NIH asthma (2007) –NIH food allergy (2010) AANMA Posters