1. Current and Novel Approaches to Treating Chondral Lesions by Timothy M. Wright, and Suzanne A. Maher J Bone Joint Surg Am Volume 91(Supplement 1):120-125 February 1, 2009 ©2009 by The Journal of Bone and Joint Surgery, Inc.

2. Schematic of the mechanical effects of the presence of a defect in articular cartilage, illustrating elevated contact pressures adjacent to the defect. Timothy M. Wright, and Suzanne A. Maher J Bone Joint Surg Am 2009;91:120-125 ©2009 by The Journal of Bone and Joint Surgery, Inc.

3. Cumulative revision rate for total knee arthroplasty (TKA) recipients in the Swedish knee registry, illustrating that patients who are less than sixty-four years of age have an increased prevalence of revision up to ten years postoperatively and, at five ye... Timothy M. Wright, and Suzanne A. Maher J Bone Joint Surg Am 2009;91:120-125 ©2009 by The Journal of Bone and Joint Surgery, Inc.

4. Autologous chondrocyte implantation (ACI) and mosaicplasty (M) for eighty patients (age eighteen to forty-five years) resulted in a 23% failure rate in both groups at five years (sixty months) postoperatively14. Timothy M. Wright, and Suzanne A. Maher J Bone Joint Surg Am 2009;91:120-125 ©2009 by The Journal of Bone and Joint Surgery, Inc.

5. Mechanical forces influence the response of cells, the effectiveness of regulators (such as growth factors), and the role that the matrix will play in enabling the generation of a viable tissue substitute. Timothy M. Wright, and Suzanne A. Maher J Bone Joint Surg Am 2009;91:120-125 ©2009 by The Journal of Bone and Joint Surgery, Inc.

6. Timothy M. Wright, and Suzanne A. Maher J Bone Joint Surg Am 2009;91:120-125 ©2009 by The Journal of Bone and Joint Surgery, Inc.

7. Timothy M. Wright, and Suzanne A. Maher J Bone Joint Surg Am 2009;91:120-125 ©2009 by The Journal of Bone and Joint Surgery, Inc.