1. Pharmacology Tutoring for Alcohol By Alaina Darby

2. Which of the following is not true of ethanol? a.It affects multiple organ systems b.It acts as a CNS stimulant c.It can impair prenatal organ development d.The mechanism for its effects are not totally understood

3. Which of the following is not true of ethanol absorption? a.Occurs via diffusion b.Most rapid from the stomach c.Impeded by food d.Occurs throughout the GI tract

4. Which of the following is true of ethanol elimination? a.95% is eliminated in breath, urine and sweat b.Ethanol is oxidized by three enzymes c.Ethanol is directly converted to acetaldehyde d.Acetaldehyde accumulates when you drink faster

5. Which of the following is the rate limiting step of ethanol metabolism? a.Conversion of ethanol to acetaldehyde by alcohol dehydrogenase b.Conversion of ethanol to acetaldehyde by aldehyde dehydrogenase c.Conversion of ethanol to acetic acid by alcohol dehydrogenase d.Conversion of ethanol to acetic acid by aldehyde dehydrogenase

6. Which of the following accumulates due to disulfram? a.Ethanol b.Acetaldehyde c.Acetic acid d.Aldehyde dehydrogenase

7. Which of the following does naltrexone inhibit? a.Ethanol activation of dopamine system b.Ethanol activation of serotonin system c.Enzymatic oxidation of ethanol to acetic acid d.Enzymatic oxidation of ethanol to acetaldehyde

8. Which of the following is not true of the action of ethanol? a.Activation of dopamine receptors b.Activation of NMDA receptors c.Activation of GABA A receptors d.Activation of BK channels e.Activation of 5-HT 3 receptors

9. Which of the following would be the least dangerous to take with ethanol due to GABA enhancement? a.Benzodiazepines b.Opioids c.Amphetamines d.Barbiturates

10. Which of the following which of the following vitamins is not inhibited by ethanol? a.Niacin b.Thiamine c.B1 d.B6

11. For which of the following conditions does ethanol have a beneficial effect? a.CHF b.Hypercholesterolemia c.Hyperglycemia d.Hypertension

12. Which of the following is an effect of both Wernicke’s encephalopathy and cerebellar degeneration? a.Dementia b.Memory loss c.Nystagmus d.Ataxia

13. Which of the following is an effect of excessive ethanol intake that may lead to shrinkages of brain matter due to thiamine deficiency? a.Pancreatitis b.Worsening of ulcers c.Flattening of intestinal villi d.Gastric bleeding

14. Which of the following is an effect of excessive ethanol on the liver that causes alcohol liver disease (ALD)? a.Increased fat accumulation in the liver b.Decreased fat accumulation in the liver c.Increased blood flow to the liver d.Decreased blood flow to the liver

15. Which of the following is not a drug used to treat alcoholism? a.Naltrexone b.Disulfiram c.Acamprosate d.Meperidine

16. Which of the following is not true of pharmacological treatment of alcoholism? a.Used to maintain abstinence b.Used to treat symptoms from alcohol c.Used to prevent relapse d.Used in combination with behavioral therapy

17. Which of the following should not be used before the patient has abstained for 12 hours? a.Naltrexone b.Disulfiram c.Acamprosate d.Meperidine

18. Which of the following may inhibit NMDA receptors or stimulate GABA receptors? a.Naltrexone b.Disulfiram c.Acamprosate d.Meperidine

19. Which of the following blocks opioid receptors? a.Naltrexone b.Disulfiram c.Acamprosate d.Meperidine

20. For which of the following does the drug block activation of dopamine neurons? a.Naltrexone b.Disulfiram c.Acamprosate d.Meperidine