Presentation is loading. Please wait.

Presentation is loading. Please wait.

Glycolysis during rest and exercise. Fates of Pyruvate Conversion to acetyl-CoA (oxidative phosphorylation) Lactate (glycolysis) AAT - increases TCA intermediates.

Published byGyles Martin Modified over 8 years ago

Similar presentations

Presentation on theme: "Glycolysis during rest and exercise. Fates of Pyruvate Conversion to acetyl-CoA (oxidative phosphorylation) Lactate (glycolysis) AAT - increases TCA intermediates."— Presentation transcript:

1 Glycolysis during rest and exercise

2 Fates of Pyruvate Conversion to acetyl-CoA (oxidative phosphorylation) Lactate (glycolysis) AAT - increases TCA intermediates

3 Exercise Higher demand for ATP --> greater activation of enzymes that regulate glycolysis PHOS PFK HK Covalently and allosterically regulated by*: Hormones Ca2+ ATP *see 2nd PowerPoint for more information

4 At higher power outputs (higher demand for ATP) -->rate of pyruvate and NADH production exceed the ability of PDH to metabolize --> lactate production

5 Intensity of Exercise

6 Flux

Download ppt "Glycolysis during rest and exercise. Fates of Pyruvate Conversion to acetyl-CoA (oxidative phosphorylation) Lactate (glycolysis) AAT - increases TCA intermediates."

Similar presentations

Glycolysis: The Central Pathway of Glucose Degradation NUTR 543 Advanced Nutritional Biochemistry Dr. David L. Gee Central Washington University.

Glycolysis: The Central Pathway of Glucose Degradation NUTR 543 Advanced Nutritional Biochemistry Dr. David L. Gee Central Washington University.
Glycolysis Glucose utilization in cells of higher plants and animals.

Glycolysis Glucose utilization in cells of higher plants and animals.
Introduction of Glucose Metabolism

Introduction of Glucose Metabolism
Three Fates of Pyruvate Pyruvate  acetyl-CoA Occurs in mitochondria Produce CO 2 and NADH + H + Pyruvate Dehydrogenase Aerobic **Acetyl-CoA used in the.

Three Fates of Pyruvate Pyruvate  acetyl-CoA Occurs in mitochondria Produce CO 2 and NADH + H + Pyruvate Dehydrogenase Aerobic **Acetyl-CoA used in the.
Pyruvate and Energetics of Glycolysis C483 Spring 2013.

Pyruvate and Energetics of Glycolysis C483 Spring 2013.
Energy Production conversion of chemical energy to mechanical energy stored in the form of ATP breakdown of ATP releases energy and produces heat –used.

Energy Production conversion of chemical energy to mechanical energy stored in the form of ATP breakdown of ATP releases energy and produces heat –used.
Gluconeogenesis : An overview

Gluconeogenesis : An overview
Overview of catabolic pathways

Overview of catabolic pathways
Chapter 9 (continued) Fermentation. glucose 2 ATP 2 NADH 2 pyruvate 2 ATP 8 NADH 2FADH 2 O 2 32-34 ATP water glycolysis citric Acid cycle oxidative phosphorylation.

Chapter 9 (continued) Fermentation. glucose 2 ATP 2 NADH 2 pyruvate 2 ATP 8 NADH 2FADH 2 O ATP water glycolysis citric Acid cycle oxidative phosphorylation.
KREBS CYCLE. Introduction Let us review fates of Pyruvate Depending on the oxidation state of the cell: Aerobic – converted to acetyl-CoA via TCA cycle.

KREBS CYCLE. Introduction Let us review fates of Pyruvate Depending on the oxidation state of the cell: Aerobic – converted to acetyl-CoA via TCA cycle.
Aulani Biokimia Presentation4 Aulanni’am Biochemistry Laboratory Chemistry Departement Brawijaya University Carbohydrate Metabolism Cont….

Aulani "Biokimia" Presentation4 Aulanni’am Biochemistry Laboratory Chemistry Departement Brawijaya University Carbohydrate Metabolism Cont….
GlycolysisGluconeogenesis. Glycolysis - Overview One of best characterized pathways Characterized in the first half of 20th century Glucose --> 2 pyruvates.

GlycolysisGluconeogenesis. Glycolysis - Overview One of best characterized pathways Characterized in the first half of 20th century Glucose --> 2 pyruvates.
A.Coupled reactions The additivity of free energy changes allows an endergonic reaction to be driven by an exergonic reaction under the proper conditions.

A.Coupled reactions The additivity of free energy changes allows an endergonic reaction to be driven by an exergonic reaction under the proper conditions.
Prentice Hall c2002Chapter 121 Chapter 12 - The Citric Acid Cycle The citric acid cycle is involved in the aerobic catabolism of carbohydrates, lipids.

Prentice Hall c2002Chapter 121 Chapter 12 - The Citric Acid Cycle The citric acid cycle is involved in the aerobic catabolism of carbohydrates, lipids.
Fig 10.5 Overview of catabolic pathways Prentice Hall c2002 Chapter 11.

Fig 10.5 Overview of catabolic pathways Prentice Hall c2002 Chapter 11.
Enzyme Nomanclature.

Enzyme Nomanclature.
Total Energy per glucose A) Cytosol – Glycolysis 2 NADH 2 ATP B) Mitochondrion – Pyruvate dehydrogenase 2 NADH --Krebs 6 NADH 2 FADH 2 2 GTP 1.

Total Energy per glucose A) Cytosol – Glycolysis 2 NADH 2 ATP B) Mitochondrion – Pyruvate dehydrogenase 2 NADH --Krebs 6 NADH 2 FADH 2 2 GTP 1.
Metabolic Pathways Most of the ATP that is generated in the body is produced through the process of oxidative phosphorylation. This process is dependent.

Metabolic Pathways Most of the ATP that is generated in the body is produced through the process of oxidative phosphorylation. This process is dependent.
Metabolism Basics Title - metabolism basics.

Metabolism Basics Title - metabolism basics.
Copyright © The McGraw-Hill Companies, Inc. Permission required for reproduction or display. 6.9 Scheme of Metabolism Slide number 1 CO 2 GLUCOSE (f) Fermentation.

Copyright © The McGraw-Hill Companies, Inc. Permission required for reproduction or display. 6.9 Scheme of Metabolism Slide number 1 CO 2 GLUCOSE (f) Fermentation.

Similar presentations

Ads by Google