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The Effect of Diet on the Human Gut Microbiome: A Metagenomic Analysis in Humanized Gnotobiotic Mice by Peter J. Turnbaugh, Vanessa K. Ridaura, Jeremiah.

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Presentation on theme: "The Effect of Diet on the Human Gut Microbiome: A Metagenomic Analysis in Humanized Gnotobiotic Mice by Peter J. Turnbaugh, Vanessa K. Ridaura, Jeremiah."— Presentation transcript:

1 The Effect of Diet on the Human Gut Microbiome: A Metagenomic Analysis in Humanized Gnotobiotic Mice by Peter J. Turnbaugh, Vanessa K. Ridaura, Jeremiah J. Faith, Federico E. Rey, Rob Knight, and Jeffrey I. Gordon Sci Transl Med Volume 1(6):6ra14-6ra14 November 11, 2009 Published by AAAS

2 Fig. 1 Design of human microbiota transplant experiments. Peter J. Turnbaugh et al., Sci Transl Med 2009;1:6ra14 Published by AAAS

3 Fig. 2 The effects of switching from the LF/PP diet to the Western diet on the humanized mouse gut microbiota. Peter J. Turnbaugh et al., Sci Transl Med 2009;1:6ra14 Published by AAAS

4 Fig. 3 Postnatal assembly of the humanized gut microbiota. Peter J. Turnbaugh et al., Sci Transl Med 2009;1:6ra14 Published by AAAS

5 Fig. 4 Clustering and taxonomic analysis of the gut microbiota of humanized mice consuming a LF/PP or Western diet. Peter J. Turnbaugh et al., Sci Transl Med 2009;1:6ra14 Published by AAAS

6 Fig. 5 Clustering of the distal gut microbiome, the C. innocuum SB23 transcriptome, and the community meta transcriptome in the ceca of humanized mice. Peter J. Turnbaugh et al., Sci Transl Med 2009;1:6ra14 Published by AAAS

7 Fig. 6 Transmissibility of adiposity from humanized mice to germ-free recipients. Peter J. Turnbaugh et al., Sci Transl Med 2009;1:6ra14 Published by AAAS


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