1. Date of download: 6/2/2016 From: Screening for Vitamin D Deficiency: A Systematic Review for the U.S. Preventive Services Task Force Ann Intern Med. 2015;162(2):109-122. doi:10.7326/M14-1659 Analytic framework. Numbers on figures indicate key questions. For a list of key questions, see the Methods section or Table 2. Figure Legend: Copyright © American College of Physicians. All rights reserved.American College of Physicians

2. Date of download: 6/2/2016 From: Screening for Vitamin D Deficiency: A Systematic Review for the U.S. Preventive Services Task Force Ann Intern Med. 2015;162(2):109-122. doi:10.7326/M14-1659 Summary of evidence search and selection. 25-(OH)D = 25-hydroxyvitamin D. * Cochrane Central Register of Controlled Trials and the Cochrane Database of Systematic Reviews. † Identified from reference lists or by hand-searching or suggested by experts. ‡ Studies that provided data and contributed to the body of evidence were considered included. Studies may have provided data for more than 1 key question or published article; 27 unique studies were included, and a total of 35 articles were included. Figure Legend: Copyright © American College of Physicians. All rights reserved.American College of Physicians

3. Date of download: 6/2/2016 From: Screening for Vitamin D Deficiency: A Systematic Review for the U.S. Preventive Services Task Force Ann Intern Med. 2015;162(2):109-122. doi:10.7326/M14-1659 Meta-analysis of effects of vitamin D treatment on mortality. To convert ng/mL to nmol/L, divide by 0.40. 25-(OH)D = serum 25-hydroxyvitamin D. * ≥90% of study participants had 25-(OH)D levels <20 ng/mL. † ≥90% of study participants had 25-(OH)D levels ≤30 ng/mL, and ≥10% had 25-(OH)D levels ≥20 ng/mL. ‡ Included an institutionalized population. § This is a nested case–control study from the Women's Health Initiative calcium-vitamin D trial (64). Figure Legend: Copyright © American College of Physicians. All rights reserved.American College of Physicians

4. Date of download: 6/2/2016 From: Screening for Vitamin D Deficiency: A Systematic Review for the U.S. Preventive Services Task Force Ann Intern Med. 2015;162(2):109-122. doi:10.7326/M14-1659 Meta-analysis of effects of vitamin D treatment on mortality, by institutionalized status. * This is a nested case–control study from the Women's Health Initiative calcium-vitamin D trial (64). Figure Legend: Copyright © American College of Physicians. All rights reserved.American College of Physicians

5. Date of download: 6/2/2016 From: Screening for Vitamin D Deficiency: A Systematic Review for the U.S. Preventive Services Task Force Ann Intern Med. 2015;162(2):109-122. doi:10.7326/M14-1659 Meta-analysis of effects of vitamin D treatment on risk for any fracture (top) or hip fracture (bottom). To convert ng/mL to nmol/L, divide by 0.40. 25-(OH)D = 25-hydroxyvitamin D. * ≥90% of study participants had 25-(OH)D levels <20 ng/mL. † Population institutionalized. ‡ ≥90% of study participants had 25-(OH)D levels ≤30 ng/mL, with ≥10% with 25-(OH)D levels ≥20 ng/mL. § This is a nested case–control study from the Women's Health Initiative calcium-vitamin D trial (64). Figure Legend: Copyright © American College of Physicians. All rights reserved.American College of Physicians

6. Date of download: 6/2/2016 From: Screening for Vitamin D Deficiency: A Systematic Review for the U.S. Preventive Services Task Force Ann Intern Med. 2015;162(2):109-122. doi:10.7326/M14-1659 Meta-analysis of effects of vitamin D treatment on risk for falls. To convert ng/mL to nmol/L, divide by 0.40. 25-(OH)D = 25-hydroxyvitamin D. * ≥90% of study participants had 25-(OH)D levels <20 ng/mL. † Population institutionalized. ‡ ≥90% of study participants had 25-(OH)D levels ≤30 ng/mL, and ≥10% had 25-(OH)D levels ≥20 ng/mL. § The calculated risk ratio is different from the one reported by the study. Figure Legend: Copyright © American College of Physicians. All rights reserved.American College of Physicians

7. Date of download: 6/2/2016 From: Screening for Vitamin D Deficiency: A Systematic Review for the U.S. Preventive Services Task Force Ann Intern Med. 2015;162(2):109-122. doi:10.7326/M14-1659 Meta-analysis of effects of vitamin D treatment on the number of falls per person. To convert ng/mL to nmol/L, divide by 0.40. 25-(OH)D = 25-hydroxyvitamin D; PY = person-year. * ≥90% of study participants had 25-(OH)D levels <20 ng/mL. † Population institutionalized. Figure Legend: Copyright © American College of Physicians. All rights reserved.American College of Physicians