1. Effect on growth of prolonged corticosteroid use for patients with Asthma in USTH Pediatric Out Patient Department

2. Authors: KIMBERLY ANG JM CARABEO ERIC JOHN MARAYAG ANGELO ONG CARMELOU MEJINO

3. Objectives: To determine if prolonged corticosteroid use inhibits/ promotes growth of patients with asthma in USTH Pediatric OPD.

4. Study Design Descriptive Cross-sectional Correlational

5. Setting University of Santo Tomas Hospital Out Patient Department Department of Pediatrics – Allergology patients

6. Subjects Qualified Pediatric Patients January 1, 2010- July 31, 2010 – Inclusion criteria Male or female Aged 1 to 14 years old Clinically diagnosed as having mild or moderate persistent controlled Asthma.

7. Subjects – Exclusion criteria chronic diseases fracture or immobilization Use of oral steroids growth disorder, or history of glaucoma or cataract height measurements outside 5-95% percentile of normal values for their age.

8. Outcome Measurements Z score ( height for age) Height Duration of Asthma Severity of Asthma

9. Methodology Acquisition of Out patient records – Demographics – Anthropometric measurements ( height, Z score height for age) – Duration of Asthma

10. ClassificationControllerReliever IntermittentNone Inhaled Beta 2 Agonist when needed Mild PersistentDaily Medications: ICS + other controllers Moderate PersistentDaily Medications: ICS + LABA + other controllers Severe PersistentDaily Multiple medications: ICS/oral CS + Long Acting dilators

11. Results N= 155 F= 67 M= 88

12. Results Fig. 2 Distribution of Subjects by Age

13. Results N= 155 Mild= 132 Mod= 23

14. Fig. 4 Pearson’s Correlation Graph

15. Pearson’s R Correlation R= - 0.11768 – Little or No correlation between Steroid Use and Height

16. Limitations Adherence to treatment Environmental Control Genetic Predisposition

17. Conclusion Prolonged corticosteroid use does not affect the growth of patients with Asthma in USTH Pediatric OPD

18. Recommendations Chronic ICS users Knemometry Severity of Asthma