1. Answer in journal: How do you think pH affects enzymes in the body? (Hint: Remember how temperature affects them??) 2/23/16 Date:2/23/16Topic:Enzyme EvolutionPage # ___

2. Today in Room 326/311… ADMIT SLIP: How do you think pH affects enzyme function? HW: Find a human trait that has evolved over time CONTENT OBJ: SW describe how and why lactose tolerance evolved over time LANG. OBJ: SW listen to video, read article, write notes and talk in pairs ANNOUNCEMENTS: Today after school!! AGENDA: pH Lab Share out Enzymes review Evolution of Lactose (intro/video) Evolution of Lactose (reading Intro to evolution/natural selection Date:2/23/16Topic:Enzyme EvolutionPage # ___

3. pH Lab Share out… what did you learn? Analysis Questions

4. Recall: Enzymes Proteins that speed up the rate of reactions Enzymes connect with substrate, and turn it into product

5. Enzyme Trends If we increase the enzyme concentration, how does that impact enzyme activity?

6. Enzyme Trends If we increase the substrate concentration, how will that impact enzyme activity?

7. Enzyme Trends If we change the temperature, how will that impact enzyme activity?

8. Enzyme Trends How does pH impact enzyme activity??? For example, the enzyme catalase works in your liver, which has a pH of about 7. How will the graph look? Draw this in journal 

9. Enzymes & You What temperature (in the environment) do you work best at? What pH do you work best at? Enzymes are the same way! They have special conditions in which they work best.

10. Evolution of Lactose Tolerance What’s lactose? Sugar found in milk What’s tolerance? The ability to digest What’s evolution? Changing of a population over time What’s the title mean??

11. Lactose Intolerance Anyone here who is lactose intolerant? Meaning you get sick when you drink milk?

12. Lactase What kind of molecule is this? How do you know?

13. Lactose Tolerance is special! Why might it be advantageous for humans to drink milk into adulthood? The ability to digest lactose evolved over time And in different populations! Let’s watch and find out… Write down a total of 5 notes: Either what you learned or questions you have.

14. Evolution of Lactose Tolerance What I learned…Questions I have…

15. Evolution of Lactose Tolerance: Video https://www.youtube.com/watch?v=MA9boI1qTu k https://www.youtube.com/watch?v=MA9boI1qTu k

16. Evolution of Lactose Tolerance: Reading Partner/triad reading protocol: Go in a circle, each person reads a paragraph until you finish. One person reads out all the questions. Split up questions so everyone must answer one Choose ONE paper to turn in, everyone must write their answer on it. Make sure to circle evidence.

17. Circle/Label Evidence!

18. Why lactose evolved Group share out What is this process called, when a trait provides an advantage, and those individuals survive and reproduce? Natural selection!!

19. Natural Selection

20. Homework Today, we researched the trait for lactose tolerance Tonight, research another human trait that has evolved over time, because it allowed us to better survive and reproduce Write a paragraph describing how and why the trait evolved over time (Use google, but write in your own words!)