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Genetics
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Mitosis Makes body cells Daughter cells are identical to parent cells Asexual 1 Diploid Cell > 2 Diploid Cells
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Meiosis Makes sex cells ( gametes, sperm/ egg) Daughter cells are different from parent cells Sexual 1 Diploid Cell > 4 Haploid Cells
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Steps of Cell Cycle Interphase Prophase Metaphase Anaphase Telophase Cytokinesis
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Interphase Cell grows (G1 and G2), DNA replicates (S)
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Prophase Chromosomes aPPear: DNA condenses into chromosomes
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Metaphase DNA in Middle of cell
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Anaphase DNA moves apart toward opposite ends of the cell
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Telophase Two Nuclei
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Cytokinesis Cell Splits, dividing into 2 cells
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Crossing Over Occurs during Meiosis, Prophase I Gives Genetic variation in sexually reproducing species
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DNA (Gene) Double stranded and Deoxyribose Made of nucleotides
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DNA Each nucleotide consists of a sugar, a phosphate, and a nitrogen base
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DNA The nitrogen bases are Adenine, Thymine, Guanine, Cytosine A pairs with T C pairs with G
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DNA Replication When 1 piece becomes 2
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RNA: Protein Synthesis Single stranded Ribose Sugar The base Uracil replaces Thymine A pairs with U C pairs with G
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3 kinds- mRNA, rRNA, tRNA mRNA- is the message, a copy of the DNA rRNA- Reads the message tRNA- takes the amino acid to the growing protein chain
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Transcription DNA makes mRNA Happens in the nucleus
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Translation RNA makes the Protein Happens at the ribosome All 3 types of RNA help
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Mutation A random change in the base (letters) Causing a protein to be made wrong or not at all.
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Non-disjuction Change in chromosome number. Ex. Down's Syndrome- a baby has 47 chromosomes instead of 46.
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DNA Technology
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Karyotype Picture of the chromosomes of the baby, can tell if baby has certain problems based on chromosome number and location
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Down Syndrome Caused by trisomy (3 chromosomes) at #21
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Gel Electrophoresis DNA fingerprint, band pattern, crime and paternity
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Transgenic Organisms/ Recombinant DNA Organism with DNA from 2 different species Example: human insulin bacteria
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Cloning Making identical genetic copies of an organism Made through Asexual Reproduction
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Punnett Squares
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Trait Characteristic Eye color, hair color
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Allele Options Brown, blue, green. Hazel eye color
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Dominant Trait the shows
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Recessive Trait that hides, unless you get it from both parents
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Homozygous/Pure Both traits are the same TT or tt
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Heterozygous/Hybrid Both traits are different Tt
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Phenotype Physical appearance Tall, Blue AA Aaaa
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Genotypes Types of genes Homozygous recessive (rr) GG – Homozygous Dominant Gg – Heterozygous Gg – Homozygous Recessive
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Special Crosses Dihybrid Cross: DDGG Codominance: Both Show Incomplete dominance: Blend/In-between Autosomal- NOT SEX linked/ NO X's Sex-linked: X-linked X B X B - Normal Girl X B X b - Carrier Girl X b X b - Affected Girl X B y – Normal Boy X b y – Affected Boy
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Sickle Cell Sickle Cell- Due to a Point Mutation causing a change in the protein resulting in a sickle shaped blood cell.
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Pedigree Are used to study a inheritance of a trait in a family
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Analyzing a Pedigree 1. Is it sex-linked (female carrier ONLY) 2. What is recessive?
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Evolution- Change over time Evolution caused by natural selection, so organisms must ADAPT to survive Charles Darwin: Father of Evolution Darwin's Ideas: Overproduction of offspring Variation Competition Survival of the Fittest
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Evidences of Evolution Fossils Comparative Anatomy
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Comparative Anatomy: Common Ancestor Homologous Structures- same structure, different function. Ex. Human arm, whale flipper, bird wind
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Comparative Anatomy Vestigial Structure- organ no longer used, gets smaller Ex. Human appendix and tailbone
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Evidences of Evolution Embryology-Comparing embryos of different species: Common Ancestor Biochemistry- comparing DNA sequences
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Evolution Time Line 1. Anaerobic, Prokaryotes 2. Photosynthetic, Prokaryotes 3. Aerobic, Prokaryotes 4. Heterotrophic Eukaryotes
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Endosymbiosis Explains How Eukaryotic Cells Evolved. A larger cell swallowed a smaller cell (Now Known as the chloroplast or mitochondrion. Evidence Mitochondrion and Chloroplasts have their own DNA
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Scientists of Evolution 1. Lamark- believed that as the environment changed the organism changed 2. Darwin- believed Natural Selection determines what organisms survive and produce offspring 3. Malthus- Human Population Growth would lead to Famine and Poverty 4. Lyell- proved the earth was older than people thought 5. Wallace- had the same ideas as Darwin, but Darwin got all the credit
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Taxonomy Kingdom: Largest Phylum Class Order Family Genus Species: Smallest
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Kingdoms Bacteria: Unicellular, prokaryotes Protists: Unicellular, eukaryotes Fungi: Multicelluar, Eukaryotic, Heterotrophs, Cell Wall, and No locomotion Plants: Multicellular, Eukaryotic, Autotrophs, Cell Wall, and No locomotion Animals: Mulicellular, Eukaryotic, Heterotrophs, and Locomotion
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Plant Parts Flowers: Used for Reproduction (Pollination) Leaf: Used for Photosynthesis Stomata: found on the leaf used for gas exchange (take in CO 2 and release O 2 ) Xylem: Vascular tissue used to move materials UP through the plant Phloem: Vascular tissue used to move materials DOWN the plant.
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Animal Kingdom Phylum Chordata: Spinal cord and backbone Class Mammalia: Live birth and Mammary Glands
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