1. Sensing Health and Disease Marc Teunis, Ph.D., Associate professor, University of Applied Sciences, Utrecht, lecturer Biology -> Immunology Data Science and R-Programming Workshop: R-Programming: www.innovativetesting.nl/cprprogrammingwww.innovativetesting.nl/cprprogramming Thursday: 17:00 – 20:00 hrs. Friday:19:00 – 22:00 hrs. Campus Party; Sensing Health1

2. Sensing health and disease Taking E-Health one step further! Integration of biomarkers in wearable Solving a prominent medical issue Hacking open data ONTOFORCE platform Campus Party; Sensing Health2 http://mareenfischinger.com/people/e-health/

3. Challenge program Thursday 26th May 12:00 - 13:00 Introductory Lecture by Dr. Jan Van Erp, TNO 13:00 - 14:00 Group formation by Drs. Henny De Vos-Burchart 16:00 - 17:00 Technology Lecture by Dr. Marc van Lieshout, TNO Friday 27th May 11:00 - 12:00 First pitches for the jury Saturday 28th May 11:00 - 12:00 Second Pitches for the jury, and awards Campus Party; Sensing Health3

4. The Challenge Multiple cases: want to bring your own case? Perfect! Multidisciplinary team (max. 8 persons) Max. 5 groups can participate Gather case information: Biology, Technology, Chemistry, Programmers Investigate possible technological platforms and applications Hack the data to obtain biomarker and disease information Prepare 7 minute pitch for Friday Prepare 7 minute pitch for Saturday: Award Campus Party; Sensing Health4

5. Case 1 - Obesity Increased incidence in the developed countries Risk for cardiovascular disease Risk for metabolic disorders Insulin resistance Campus Party; Sensing Health5 Samsung patent: Body fat can be measured by bioelectrical impedance Read more: http://www.dailymail.co.uk/sciencetech/article-3162213/Forget-heart-monitors- pedometers-Samsung-just-patented-way-measure-BODY-FAT-using-just- smartphone.html#ixzz49hL3qTCehttp://www.dailymail.co.uk/sciencetech/article-3162213/Forget-heart-monitors- pedometers-Samsung-just-patented-way-measure-BODY-FAT-using-just- smartphone.html#ixzz49hL3qTCe

6. Case 2 - Melanoma Increased incidence in Caucasian populations Early detection is important Under- and over diagnosed If undetected is life threatening Campus Party; Sensing Health6

7. ONTOFORCE Data and text mining applications URL: www.disqover.comwww.disqover.com LOGIN: will be sent after enrolling into the challenge PASSWORD: will be sent after enrolling to Challenge Tutorial: https://www.youtube.com/watch?v=bdMlSOS9-yIhttps://www.youtube.com/watch?v=bdMlSOS9-yI sent email to: info@ontoforce.com and you will get a login accountinfo@ontoforce.com Demo: This afternoon during ‘Tech Lecture’ at 16:00 hrs. Campus Party; Sensing Health7 http://ontoforce.tumblr.com/

8. Coaches Six Coaches are present for consult on Thursday and Friday: Dr. Ellen Hilhorst (Chemistry) Dr. Raymond Pieters (Immunologist) Drs Shirley Kartaram (Human studies) Steven Vanderschaeve (Data Science - ONTOFORCE) Paulo Van Huffel (Data Science - ONTOFORCE) Dr. Marc Teunis (Animal studies / R - programming) Coach contact E-mail for appointments, pitch presentations and guidance: sensinghealthcp@gmail.comsensinghealthcp@gmail.com Ask for feedback on pitches Let the coaches know where your team is Register your email address if you want to participate Campus Party; Sensing Health8

9. The award The team members of the best team in terms of: Feasibility Focus Business idea Technology implemented Relevance wins the award: Campus Party; Sensing Health9

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11. Melanoma websites and datasets http://www.noo.org.uk/visualisation http://www.popsci.com/science/article/2011-01/new-handheld- melanoma-scanner-instantly-identifies-skin-cancers-laser-light http://www.popsci.com/science/article/2011-01/new-handheld- melanoma-scanner-instantly-identifies-skin-cancers-laser-light http://www.inside-r.org/r-doc/mass/Melanoma https://biometry.nci.nih.gov/cdas/datasets/plco/11/ Use the information to pitch: 1.What? 2.Reason to believe 3.How? Campus Party; Sensing Health11

12. Obesity websites and datasets http://obesitychallenge.rewiredstate.org/data http://www.noo.org.uk/visualisation Use the information to pitch: 1.What? 2.Reason to believe? 3.How? Campus Party; Sensing Health12

13. The Solution The solution is not fixed Can be a web interface or an interactive website Can be an App or dedicated software Can be a device or an integrated sensor Or a combination of all the above Or….something entirely different! Campus Party; Sensing Health13

14. Sensor technology Apple ResearchKit http://appleinsider.com/articles/15/10/15/apple-partners- with-hospitals-for-new-researchkit-studies-on-autism-epilepsy- melanoma