1. Results of statistic research in BioEnterics Intragastric Balloon System presented on II Medical Conference for the Surgery of Obesity in Poland Pulsmed Hospital in Lodz www.pulsmed.com.pl 15-17 October 2004 Zabrze-Wisla

2. BioEnterics Intragastric Balloon System is indicated for temporary use in weight – loss therapy Pulsmed Hospital in Lodz www.pulsmed.com.pl

3. Aims How BIB System is used for weight loss in obese and severely obese patients?

4. Materials and methods Intragastric Balloon BIB System - -/Bioenterics Intragastric Balloon INAMED, CA/ The BIB System balloon is placed in the stomach of 151 patients for 180 days Women - 99, Men - 52

5. Materials and methods Patients’ weight 78 - 215 kg An average weight 113.8 kg BMI /an average/ 39.4 kg/m 2

6. Women-age

7. Men-age

8. Women/Men

9. BIB System Placement and Inflaction The patient is prepared according to hospital protocol for gastroscopy /short intravenous anaesthetization/ Fill the balloon 480-680 ml 0,9% NaCl coloured blue

10. Rekommendation after intervention Diet to 1200 kcal with low IG /glycemic index/ More physical activity Healthy eating program

11. Results Weight loss in all patients /148/ An average weight loss 24.6 kg during 180 days /21.6% weight/ An average overweight reduce 59.1%

12. An average weight loss /kg/

14. Treatment: 2-3 days gastric discomfort, feeling of nausea and vomiting following balloon placement as the digestive system adjusts to the presence of the balloon /95% patients/ Heartburn - temporary Relapse into gastric discomfort – 2 patients /1.3%/ Balloon Replacement before 180 days – 4 patients /2- intolerance, 2 – at patient’s own request/

15. Complications: There are no serious complications after the use of the BIB System In one case the balloon was removed because of small demage of mucous membrane of cardia gastris

16. Conclusion: The BIB System is indicated in weight – loss therapy for obese patients who have significant health risk related to their obesity and who have failed to achieve and maintain weight loss with a supervised weight-control program. The risk of balloon deflation and intestinal obstruction is significantly low when balloon is removed at the time of 6 months or earlier.

17. BIB System 13.085 kg 2.826 kg Literature: *Own sources *INAMED HEALTH brochure „BioEnterics Intragastric Balloon System” 15-17 October 2004