1. Curing Cancer with Alfresco and the American Society for Clinical Pathologists Ron Swan CTO Ray Wijangco Alfresco Practice Manager

2. Agenda About ASCP Solution Overview Roadmap Architecture Overview

3. What is Pathology? pa·thol·o·gy noun: the study of diseases and of the changes that they cause : changes in a person, an animal, or a plant that are caused by disease 18,000 Practicing Pathologists in US Average age is 50 years and increasing Representing 70-80% of the world’s total Roughly 70-80% of disease diagnosis comes from a laboratory

4. Problems facing Pathology Medical errors Missed 1 st opinions Misclassification of diagnoses Wait times for diagnosis are increasing in some cases Market Forces Greater access to healthcare Decreasing number of laboratory healthcare providers

5. Solution Overview

6. ASCP Alfresco Applications Asset Warehouse Alfresco Share Asset Warehouse Alfresco Share Vault Web Indexing Interface Vault Web Indexing Interface ASCPedia Consumer Search ASCPedia Managed by Asset Administrator to start workflows / upload assets Experts index content by discipline, including workflow review by peers and admin. Consumer search interface to access images

7. Our history with Alfresco 2008 - Initial development of Asset Library using Alfresco Community 2012 - Rewrite of the Asset Library using Alfresco Enterprise 2014 – Development of ASCPedia

8. Asset Warehouse Librarian / Admin Tool OOTB Alfresco Share Manage Contributions Prepare / Organize Unindexed Assets Apply / Admin Metadata Start Indexing Workflows

9. Vault Web Asset Indexing Tool Bulk Indexing Annotations Pathology Terms / Tagging Workflow Peer Review Process Final Admin Approval Based on Expertise

10. ASCPedia

11. Challenges of working in a lab Workflow issues Glass slides break or are lost Comparisons to previous patient specimens are challenging Hoarding of reference slides Remote Diagnosis Slides often need to be shipped to an expert Lack of real time collaboration

12. Opportunities in Pathology Pathology is becoming digital Full Slide Scans ~3gb an image Crowdsourcing & sharing have become mainstream Virtual Training Shared Viewing Image Annotations Machine Learning Image comparison Clinical Decision Support

13. Interesting Features

14. Crowdsourcing

15. Annotations

16. Curated Collections

17. Google Glass Integration Prototype

18. Roadmap

19. Image Analysis Cross referencing images Pathology to Radiology Time lapse To known abnormalities

20. Image Recognition Applying facial recognition software to your biopsy

21. "Clinical Decision Support systems link health observations with health knowledge to influence health choices by clinicians for improved health care” - Robert Hayward of the Centre for Health Evidence

22. Other possibilities Case management tool Provide medical knowledge and diagnosis to countries in need. Collaborative Viewing Allow experienced Pathologists to virtually train others

23. Architecture Overview

24. High Level Architecture

25. Vault Web Architecture Custom Java Spring MVC Activiti / Workflow Driven TSG OpenAnnotate for Asset Annotations Integration with PathTerms for Medical Keywords Authentication with ASCP’s CRM

26. ASCPedia Architecture Single Page App / Backbone.js External Solr for Search / Metadata Published metadata from Alfresco Repository Access content via Alfresco WebScripts Integration with CRM

27. Demo

28. Question & Answers

29. Thank You!