1. Your Body’s Espresso…Blood APL3

2. General Characteristics Liquid connective tissue: composed of –Formed elements – RBC, WBC, platelets –Plasma (yellowish), mainly H 2 O, also contains; proteins, electrolytes, etc. Blood volume: –Avg. male = 5-6 liters –Avg. female = 4-5 liters pH range is 7.35 – 7.45 (slightly alkaline) Viscosity due to RBC

3. Functions (3) 1.Acts as transport medium -Delivers nutrients, O2, & hormones to cells 2.Part of body’s defense mechanism -Leukocytes & antibodies protect 3.Helps to regulate body (homeostasis) -Aids in temp regulation & acts as pH buffer

4. Origin of Blood Formed in bone marrow from hemapoetic stem cells (progenitor cells) If stay in bone marrow, lead to erythrocytes Some migrate to Thymus, lead to leukocytes Thymus will be absorbed by age 30.

5. Absence of Thymus Creates an inability to produce T-cells (these are the main defense mechanism against viruses and some bacteria) –CD-8 T-cell (fights virus) –CD-4 T-cell (aids macropages and antibodies in battling bacteria) Severly Combined Immuno-Defiecency (SCID) “Boy in the Bubble”

6. Erythrocytes Most abundant 4.6 – 6.2 million/mm3 Biconcave disk, lacking nucleus Contains Hemoglobin Protein containing Fe Life span: 120 days

7. Leukocytes 5K – 10K / mm3 blood FXN: engulf and destroy bacteria, results in pus formation Life span: 20 days or less Possess a nucleus Five types Different type dues to different “infection”

8. Platelets (thrombocytes) Tiny fragment of cell (1/10 th size of RBC) 150K – 360K/mm3 blood Formed from stem cells Function: Formation of blood clots

10. Neutrophil (60%) Function as…

11. Basophils (1%) Function: Release…

12. Eosinophils (1%) Function against?Relation to

13. Lymphocytes (25-33%) FunctionDiseases related

14. Monocytes (3-8%) FunctionDiseases related