1. WARM UP “Give what you have. To someone else, it may be better than you dare to think.” –Henry Wordsworth Longfellow 1.What does this quote mean to you? 2.How can you apply this to DNA/RNA/protein structure and function 3.How can you apply this to the long process of discovering DNA and its structure?

2. Molecular Evolution

3. Central Dogma DNA RNA Protein Trait Proteins create traits that DNA and RNA code for TranscriptionTranslation Expression

4. Mutations A change in DNA sequence Affect RNA, proteins, and traits

5. Types of Mutations Substitution – Change base Frameshift – Deletion or addition – Changes “reading frame”

6. Types of Mutations

7. DNA and Evolution Variations in DNA create variations in traits – Mutations are the source of variation Mutations are the only way to get new traits Traits passed down through DNA – Variation in offspring

8. Mutations and Microevolution Natural selection determines whether mutations will be passed on – Advantageous Evolution – Lethal Extinction – Neutral Genetic drift

9. Mutations and Macroevolution New trait from advantageous mutation 2 different traits…..2 different species…..

10. WRAP UP 1.List 3 types of mutations, and describe the impact of each on the DNA code in 3 words.

11. WARM UP Explain how the discovery of the structure of DNA, and the way it copies itself, supports Darwin’s ideas about traits being passed on from parents to offspring.

12. WRAP UP Describe how you think mutations might affect evolution (if at all).