1. Okemos High School Okemos MI kelly.carrier@okemosschools.net Biology Kelly Carrier

2. Structure, Replication, Protein Synthesis DNA

3. DNA vs RNA DNA Double Stranded Exists in eukaryotes Composed of Phosphate Sugar Base- Adenine, Guanine, Thymine, Cytosine Bases are in groups: Purines Pyrimidines RNA Single Stranded Exists in BOTH eukaryotes and prokaryotes Composed of Phosphate Sugar Base-Adenine, Guanine, Cytosine, URACIL

4. DNA vs RNA

6. http://www.johnkyrk.com/DNAanatomy.swf

7. DNA Purine Adenine Guanine Pyrimidines Th y mine C y tosine Base Pairing Rule?

8. DNA Replication

9. Central Idea of DNA Replication DNA replicates during Sphase Helicase splits DNA Polymerase places new base pairs from 3 to 5 on original and 5-3 on new strand Leading strand goes along with the helicase Lagging strand DNA polymerase goes in the opposite direction…Okazaki fragments

10. Video Review http://www.youtube.com/watch?v=teV62zrm2P0

11. DNA Replication

12. Protein Synthesis DNA RNA Protein

13. DNA to Protein DNA is a genetic code for proteins (the stuff that makes up you). TransC occurs in the nucleus mRNA TransL occurs outside the nucleus mRNa translated and amino acids join to make up protein

14. Protein Synthesis

18. DNA RNA Protein Inside nucleus Transcription DNA unwinds RNA Polymerase is an enzyme which initiates the building of mRNA. mRNA binds to the DNA complement with AGC U instead of T mRNA snakes out of the nucleus mRNA carries the message to the ribosome

19. Outside nucleus Translation mRNA is ‘read’ by the tRNA which brings in amino acids according to the mRNA sequence. Amino acids are connected by peptide bonds making a protein.

20. Protein Synthesis Overview