1. LO: SWBAT explain how DNA replicates DN: h/0 DNA regents questions HW: read pp295-299 Castle Learning

2. DNA Replication To make a copy Replicacion de ADN- La palabra replicacion significa copiar What does REPLICATE mean?

3. What do we get when DNA replicates? DNA Replication + Two New DNA Molecules

4. DNA Structure Review What is DNA composed of? Nucleotides 4 types Adenine Thymine Guanine Cytosine Deoxyribose

5. How do the Bases Pair Up? Como se unen los pares? A-T G-C H Bonds

6. DNA Structure What shape is this? Double-Helix El ADN tiene la forma de una helice doble. What scientists shared the Nobel Prize for their work on DNA? Maurice Wilkins Watson & Crick Rosalind Franklin

7. Esto ocurre en nuestros cuerpos para crecer y reparar GROWTH REPAIR Antes de que la celula se divida el DNA debe replicarse.

9. Steps of DNA Replication/ Pasos para la replicacion de ADN G - C C - G T - A A - T T - A DNA Molecule Bonds Broken G C C G T A A T T A 2 Separate Strands Step 1: Bonds between the bases are broken and the DNA Molecule is “Unzipped” Se rompen los enlaces y la molecula de abre como un zipper Enzymes

10. Step 2: Individual bases find their “match” on each single strand of DNA. Se completa cada linea con la ayuda de una enzima G C C G T A A T T A 2 Separate Strands Base Pairing GCTATGCTAT C G A T A CGATACGATA G C T A T Each strand is a Template for base pairing Enzymes DNA Polymerase

11. Step 3: Bonds between the bases are formed Se forman los enlaces G C C G T A A T T A Bonds Formed G - C C - G T - A A - T T - A

12. DNA Replication G - C C - G T - A A - T T - A DNA Molecule G C C G T A A T T A 2 Separate Strands G - C C - G T - A A - T T - A Bonds Broken Base Pairing What is formed? 2 Identical DNA Molecules

13. What Process is this? DNA Replication Each strand serves as a Template

14. Summary Questions 1)Do you think DNA Replication is an accurate process? Why? 2)What do you think would happen if DNA did not accurately replicate? 3)What are some of the consequences? 4)DNA Replication AnimationDNA Replication Animation