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Telomere-Maintenance Mechanisms in Soft-Tissue Malignant Fibrous Histiocytomas by Toshihiro Matsuo, Jerry W. Shay, Woodring E. Wright, Eiso Hiyama, Shoji.

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Presentation on theme: "Telomere-Maintenance Mechanisms in Soft-Tissue Malignant Fibrous Histiocytomas by Toshihiro Matsuo, Jerry W. Shay, Woodring E. Wright, Eiso Hiyama, Shoji."— Presentation transcript:

1 Telomere-Maintenance Mechanisms in Soft-Tissue Malignant Fibrous Histiocytomas by Toshihiro Matsuo, Jerry W. Shay, Woodring E. Wright, Eiso Hiyama, Shoji Shimose, Tadahiko Kubo, Takashi Sugita, Yuji Yasunaga, and Mitsuo Ochi J Bone Joint Surg Am Volume 91(4):928-937 April 1, 2009 ©2009 by The Journal of Bone and Joint Surgery, Inc.

2 Illustration depicting the evaluation of surgical margins according to the method of Kawaguchi et al.34. Toshihiro Matsuo et al. J Bone Joint Surg Am 2009;91:928- 937 ©2009 by The Journal of Bone and Joint Surgery, Inc.

3 Kaplan-Meier curve illustrating the association between survival rate and ALT status in patients with malignant fibrous histiocytoma. Toshihiro Matsuo et al. J Bone Joint Surg Am 2009;91:928- 937 ©2009 by The Journal of Bone and Joint Surgery, Inc.

4 Kaplan-Meier curves showing the survival rates for patients with malignant fibrous histiocytoma samples that were ALT-negative and telomerase-positive, ALT-positive and telomerase-negative, and ALT-negative with different levels of telomerase activity. Toshihiro Matsuo et al. J Bone Joint Surg Am 2009;91:928- 937 ©2009 by The Journal of Bone and Joint Surgery, Inc.

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