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5-aza-2′-deoxycytidine-mediated c-myc Down-regulation Triggers Telomere-dependent Senescence by Regulating Human Telomerase Reverse Transcriptase in Chronic.

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Presentation on theme: "5-aza-2′-deoxycytidine-mediated c-myc Down-regulation Triggers Telomere-dependent Senescence by Regulating Human Telomerase Reverse Transcriptase in Chronic."— Presentation transcript:

1 5-aza-2′-deoxycytidine-mediated c-myc Down-regulation Triggers Telomere-dependent Senescence by Regulating Human Telomerase Reverse Transcriptase in Chronic Myeloid Leukemia Cindy Grandjenette, Michael Schnekenburger, Tommy Karius, Jenny Ghelfi, Anthoula Gaigneaux, Estelle Henry, Mario Dicato, Marc Diederich Neoplasia Volume 16, Issue 6, Pages 511-528 (June 2014) DOI: 10.1016/j.neo.2014.05.009 Copyright © 2014 Neoplasia Press, Inc. Terms and Conditions Terms and Conditions

2 Figure 1 Neoplasia 2014 16, 511-528DOI: (10.1016/j.neo.2014.05.009) Copyright © 2014 Neoplasia Press, Inc. Terms and Conditions Terms and Conditions

3 Figure 1 Neoplasia 2014 16, 511-528DOI: (10.1016/j.neo.2014.05.009) Copyright © 2014 Neoplasia Press, Inc. Terms and Conditions Terms and Conditions

4 Figure 1 Neoplasia 2014 16, 511-528DOI: (10.1016/j.neo.2014.05.009) Copyright © 2014 Neoplasia Press, Inc. Terms and Conditions Terms and Conditions

5 Figure 1 Neoplasia 2014 16, 511-528DOI: (10.1016/j.neo.2014.05.009) Copyright © 2014 Neoplasia Press, Inc. Terms and Conditions Terms and Conditions

6 Figure 1 Neoplasia 2014 16, 511-528DOI: (10.1016/j.neo.2014.05.009) Copyright © 2014 Neoplasia Press, Inc. Terms and Conditions Terms and Conditions

7 Figure 1 Neoplasia 2014 16, 511-528DOI: (10.1016/j.neo.2014.05.009) Copyright © 2014 Neoplasia Press, Inc. Terms and Conditions Terms and Conditions

8 Figure 2 Neoplasia 2014 16, 511-528DOI: (10.1016/j.neo.2014.05.009) Copyright © 2014 Neoplasia Press, Inc. Terms and Conditions Terms and Conditions

9 Figure 2 Neoplasia 2014 16, 511-528DOI: (10.1016/j.neo.2014.05.009) Copyright © 2014 Neoplasia Press, Inc. Terms and Conditions Terms and Conditions

10 Figure 2 Neoplasia 2014 16, 511-528DOI: (10.1016/j.neo.2014.05.009) Copyright © 2014 Neoplasia Press, Inc. Terms and Conditions Terms and Conditions

11 Figure 2 Neoplasia 2014 16, 511-528DOI: (10.1016/j.neo.2014.05.009) Copyright © 2014 Neoplasia Press, Inc. Terms and Conditions Terms and Conditions

12 Figure 3 Neoplasia 2014 16, 511-528DOI: (10.1016/j.neo.2014.05.009) Copyright © 2014 Neoplasia Press, Inc. Terms and Conditions Terms and Conditions

13 Figure 4 Neoplasia 2014 16, 511-528DOI: (10.1016/j.neo.2014.05.009) Copyright © 2014 Neoplasia Press, Inc. Terms and Conditions Terms and Conditions

14 Figure 4 Neoplasia 2014 16, 511-528DOI: (10.1016/j.neo.2014.05.009) Copyright © 2014 Neoplasia Press, Inc. Terms and Conditions Terms and Conditions

15 Figure 4 Neoplasia 2014 16, 511-528DOI: (10.1016/j.neo.2014.05.009) Copyright © 2014 Neoplasia Press, Inc. Terms and Conditions Terms and Conditions

16 Figure 5 Neoplasia 2014 16, 511-528DOI: (10.1016/j.neo.2014.05.009) Copyright © 2014 Neoplasia Press, Inc. Terms and Conditions Terms and Conditions

17 Figure 5 Neoplasia 2014 16, 511-528DOI: (10.1016/j.neo.2014.05.009) Copyright © 2014 Neoplasia Press, Inc. Terms and Conditions Terms and Conditions

18 Figure 6 Neoplasia 2014 16, 511-528DOI: (10.1016/j.neo.2014.05.009) Copyright © 2014 Neoplasia Press, Inc. Terms and Conditions Terms and Conditions

19 Figure 7 Neoplasia 2014 16, 511-528DOI: (10.1016/j.neo.2014.05.009) Copyright © 2014 Neoplasia Press, Inc. Terms and Conditions Terms and Conditions

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