1. 1 Common Names of Heterocyclic Amines If the nitrogen atom occurs as part of a ring, the compound is designated as being heterocyclic Each ring system has its own parent name

2. 2

3. 3 Table 24-1a, p. 923

4. 4 Table 24-2, p. 926

5. 5 S N 2 Reactions of Alkyl Halides Ammonia and other amines are good nucleophiles

6. 6 Uncontrolled Multiple Alkylation Primary, secondary, and tertiary amines all have similar reactivity, the initially formed monoalkylated substance undergoes further reaction to yield a mixture of products

7. 7 Mechanism of Reductive Amination

8. 8 Reductive Amination Is Versatile Ammonia, primary amines, and secondary amines yield primary, secondary, and tertiary amines, respectively

9. 9 Reductive Amination of Aldehydes and Ketones Treatment of an aldehyde or ketone with ammonia or an amine in the presence of a reducing agent

10. 10 24.7 Reactions of Amines Alkylation and acylation have already been presented Fast Slow

11. 11 Hoffman Elimination Good Leaving Group E2

12. 12 Get Hoffman pdt not Zaitsev pdt.

13. 13 24.9 Heterocycles A heterocycle is a cyclic compound that contains atoms of two or more elements in its ring, usually C along with N, O, or S

14. 14 Polycyclic Heterocycles

15. 15 IR of Amines

16. 16