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Date of download: 6/9/2016 From: Antipsychotics in Adults With Schizophrenia: Comparative Effectiveness of First-Generation Versus Second-Generation Medications:

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Presentation on theme: "Date of download: 6/9/2016 From: Antipsychotics in Adults With Schizophrenia: Comparative Effectiveness of First-Generation Versus Second-Generation Medications:"— Presentation transcript:

1 Date of download: 6/9/2016 From: Antipsychotics in Adults With Schizophrenia: Comparative Effectiveness of First-Generation Versus Second-Generation Medications: A Systematic Review and Meta-analysis Ann Intern Med. 2012;157(7):498-511. doi:10.7326/0003-4819-157-7-201210020-00525 Summary of evidence search and selection. Figure Legend: Copyright © American College of Physicians. All rights reserved.American College of Physicians

2 Date of download: 6/9/2016 From: Antipsychotics in Adults With Schizophrenia: Comparative Effectiveness of First-Generation Versus Second-Generation Medications: A Systematic Review and Meta-analysis Ann Intern Med. 2012;157(7):498-511. doi:10.7326/0003-4819-157-7-201210020-00525 Positive symptoms (SAPS): haloperidol versus olanzapine. IV = inverse variance; SAPS = Scale for the Assessment of Positive Symptoms. Figure Legend: Copyright © American College of Physicians. All rights reserved.American College of Physicians

3 Date of download: 6/9/2016 From: Antipsychotics in Adults With Schizophrenia: Comparative Effectiveness of First-Generation Versus Second-Generation Medications: A Systematic Review and Meta-analysis Ann Intern Med. 2012;157(7):498-511. doi:10.7326/0003-4819-157-7-201210020-00525 Negative symptoms (PANSS and SANS): haloperidol versus olanzapine. IV = inverse variance; PANSS = Positive and Negative Syndrome Scale; SANS = Scale for the Assessment of Negative Symptoms. Figure Legend: Copyright © American College of Physicians. All rights reserved.American College of Physicians

4 Date of download: 6/9/2016 From: Antipsychotics in Adults With Schizophrenia: Comparative Effectiveness of First-Generation Versus Second-Generation Medications: A Systematic Review and Meta-analysis Ann Intern Med. 2012;157(7):498-511. doi:10.7326/0003-4819-157-7-201210020-00525 Global rating and total symptom score improvement (PANSS): haloperidol versus olanzapine. IV = inverse variance; PANSS = Positive and Negative Syndrome Scale. Figure Legend: Copyright © American College of Physicians. All rights reserved.American College of Physicians

5 Date of download: 6/9/2016 From: Antipsychotics in Adults With Schizophrenia: Comparative Effectiveness of First-Generation Versus Second-Generation Medications: A Systematic Review and Meta-analysis Ann Intern Med. 2012;157(7):498-511. doi:10.7326/0003-4819-157-7-201210020-00525 Global rating and total symptom score improvement (PANSS): haloperidol versus risperidone (with outlier). IV = inverse variance; PANSS = Positive and Negative Syndrome Scale. Figure Legend: Copyright © American College of Physicians. All rights reserved.American College of Physicians

6 Date of download: 6/9/2016 From: Antipsychotics in Adults With Schizophrenia: Comparative Effectiveness of First-Generation Versus Second-Generation Medications: A Systematic Review and Meta-analysis Ann Intern Med. 2012;157(7):498-511. doi:10.7326/0003-4819-157-7-201210020-00525 Global rating and total symptom score improvement (PANSS): haloperidol versus risperidone (outlier removed). IV = inverse variance; PANSS = Positive and Negative Syndrome Scale. Figure Legend: Copyright © American College of Physicians. All rights reserved.American College of Physicians

7 Date of download: 6/9/2016 From: Antipsychotics in Adults With Schizophrenia: Comparative Effectiveness of First-Generation Versus Second-Generation Medications: A Systematic Review and Meta-analysis Ann Intern Med. 2012;157(7):498-511. doi:10.7326/0003-4819-157-7-201210020-00525 Global rating and total symptom score improvement (BPRS): chlorpromazine versus clozapine. BPRS = Brief Psychiatric Rating Scale; IV = inverse variance. Figure Legend: Copyright © American College of Physicians. All rights reserved.American College of Physicians

8 Date of download: 6/9/2016 From: Antipsychotics in Adults With Schizophrenia: Comparative Effectiveness of First-Generation Versus Second-Generation Medications: A Systematic Review and Meta-analysis Ann Intern Med. 2012;157(7):498-511. doi:10.7326/0003-4819-157-7-201210020-00525 General psychopathology (MADRS): haloperidol versus olanzapine. IV = inverse variance; MADRS = Montgomery–Asberg Depression Rating Scale. Figure Legend: Copyright © American College of Physicians. All rights reserved.American College of Physicians

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