1. Shinagawa LASIK Center Evaluation of Functional Near Vision by Presbyopic Patients Implanted With Small Aperture Inlay Evaluation of Functional Near Vision by Presbyopic Patients Implanted With Small Aperture Inlay Mitsutoshi Ito, MD, PhD, Satoshi Yukawa, MD Takahiro Yamamoto, MD, Keigo Sekiya. MD, PhD, Minoru Tomita, MD, PhD Financial Disclosure ： Travel expenses to ASCRS for the primary author paid for by AcuFocus.

2. Disclaimer The KAMRA inlay is an investigational device in the US. It is limited by US federal law to investigational use. Shinagawa LASIK Center

3. Purpose Patient survey of functionality of near vision with the KAMRA inlay. 1.6mm Aperture 3.8mm Total diameter 5 μ Thick 8,400 Holes (5-11µ) 8,400 Holes (5-11µ) Made from Polyvinylidene Fluoride (PVDF) Inlay Design Shinagawa LASIK Center

4. Methods Patients at Shinagawa LASIK Center who had undergone the KAMRA inlay procedure were asked to take a short survey on an iPad. The survey focused on the patient’s ability to perform everyday near tasks without glasses. Shinagawa LASIK Center

5. Depth of Focus The inlay uses small aperture technology to extend depth of focus and improve near vision in presbyopic patients without limiting distance vision. Presbyopia With Inlay Inlay Lens cannot accommodate Shinagawa LASIK Center

6. Patient Demographics 245 patients surveyed at various post-op visits.

7. Results SURVEY QUESTION: Using both eyes, are you able to perform the following everyday tasks without glasses in normal lighting conditions? See numbers on mobile phone or text messages? Yes92% No8% N=245 Shinagawa LASIK Center

8. Results SURVEY QUESTION: Using both eyes, are you able to perform the following everyday tasks without glasses in normal lighting conditions? View computer screen? Yes90% No10% N=217 Shinagawa LASIK Center

9. Results SURVEY QUESTION: Using both eyes, are you able to perform the following everyday tasks without glasses in normal lighting conditions? Read store shelf price? Yes93% No7% N=237 Shinagawa LASIK Center

10. Results SURVEY QUESTION: How often do you use reading glasses? How often do you use reading glasses? None or almost none of the time 84% Some of the time13% Most of the time or almost all of the time 3% N=245 Shinagawa LASIK Center

11. Conclusion The KAMRA inlay successfully provided functional near vision in this cohort of patients. Shinagawa LASIK Center