1. BREAST CANCER IS A DISEASE OF THE DEVELOPED WORLD POLINA USTYUZHANINA 1 EN 117 LINNEUNIVERSITETET MODULE 3 VT-13

2. ANGELINA JOLIE DECIDED TO MAKE A PREVENTIVE DOUBLE MASTECTOMY IN ORDER TO REDUCE A CHANCE OF DEVELOPING BREAST CANCER. SHE INHERITED A MUTATED BRCA 1 GENE FROM HER MOTHER. BREAST CANCER www.verastic.com Polina Ustyuzhanina. Linneuniversitetet

3. MUTATIONS OF DNA AND A FAMILIAL HISTORY ARE RARE. SEVERAL RISK FACTORS HAVE BEEN WELL DOCUMENTED. RISK FACTORS Polina Ustyuzhanina. Linneuniversitetet

4. THE RISK OF DEVELOPING BREAST CANCER IS HIGHER IN THE DEVELOPED WORLD THAN IN THE MIDDLE- AND LOW-INCOME COUNTRIES HUMAN AND ECONOMIC PROGRESS AS WELL AS DEVELOPMENT OF MEDICINE AND SCIENCE RISK FACTORS Polina Ustyuzhanina. Linneuniversitetet

5. BREAST CANCER IS THOUGHT TO BE A DISEASE OF THE DEVELOPED WORLD. BREAST CANCER Polina Ustyuzhanina. Linneuniversitetet Source: World Health Organization

6. AGE THE LONGER WE LIVE, THE MORE CANCER-CAUSING FAULTS WE ACCUMULATE IN OUR DNA. THE HIGHEST RISK OF DEVELOPING BREAST CANCER IS AFTER THE AGE OF 70. LIFE EXPECTANCY Low income countries: 60 Lower middle income: 66 Upper middle income: 74 High income: 80 Source: World Health Organization Polina Ustyuzhanina. Linneuniversitetet

7. WESTERN LIFESTYLE 21% OF ALL BREAST CANCER DEATHS WORLDWIDE ARE ATTRIBUTABLE TO ALCOHOL USE, OVERWEIGHT AND OBESITY, AND PHYSICAL INACTIVITY. 27% IN HIGH-INCOME COUNTRIES (OVERWEIGHT AND OBESITY, FOR THE MOST PART). 18% IN LOW- AND MIDDLE INCOME COUNTRIES (PHYSICAL INACTIVITY, FOR THE MOST PART). Polina Ustyuzhanina. Linneuniversitetet

8. REPRODUCTIVE HABITS LATE AGE AT FIRST CHILDBIRTH AND REFUSAL TO BREASTFEED Polina Ustyuzhanina. Linneuniversitetet HIGH RISK

9. REPRODUCTIVE HABITS INCREASING: 3% FOR EACH YEAR AN ADULT WOMAN DELAYS BECOMING A MOTHER. DECREASING: 4% FOR EVERY 12 MONTHS OF BREASTFEEDING. Polina Ustyuzhanina. Linneuniversitetet

10. AFRICAN WOMEN ARE FOUR TIMES LESS LIKELY TO GET BREAST CANCER. THEY HAVE CHILDREN AT A YOUNGER AGE, HAVE MORE OF THEM AND BREASTFEED THEM LONGER. REPRODUCTIVE HABITS Polina Ustyuzhanina. Linneuniversitetet

11. A DISEASE OF THE DEVELOPED WORLD THE IMPORTANT AND WELL- DOCUMENTED RISK FACTORS: OLD AGE; CHANGES IN LIFESTYLE; CHANGES IN REPRODUCTIVE HABITS. Polina Ustyuzhanina. Linneuniversitetet

12. Cancer Research UK, 2009. What Causes Cancer? London: Cancer Research UK. Available at: [Accessed 21 May 2013] Carter, B. 2013. Breast Cancer: What Is the Risk? [online] Available at: [Accessed 21 May 2013] World Health Organization, 2008-2013? Breast Cancer: Prevention and Control. Geneva: World Health Organization. Available at: [Accessed 21 May 2013] World Health Organization, 2011? Life Expectancy: Life Expectancy by World Bank Income Group. Geneva: World Health Organization. Available at: [Accessed 23 May 2013]http://www.cancerresearchuk.org/cancer-info/cancerandresearch/all-about-cancer/what-is-cancer/what- causes-cancer/http://www.bbc.co.uk/news/magazine- 22570274http://www.who.int/cancer/detection/breastcancer/en/index.htmlhttp://apps.who.int/gho/data/view.main.700?lang=en REFERENCE LIST Polina Ustyuzhanina. Linneuniversitetet

13. THANK YOU! Polina Ustyuzhanina. Linneuniversitetet