2. Digestion vs Absorption? Why digest food? What doesn’t need to be digested?

3. How does food get digested? Chief Cells – pepsinogen Chief Cells – replaced every 3-4 days Parietal Cells – HCl and intrinsic factor Intrinsic factor – makes Vitamin B12 absorbable (in the small intestine)

4. Enzymes “Enzyme”ProducedWhere it worksHow it works Salivary amylase Pancreatic amylase Maltase Lactase Pepsin Pepsinogen Trypsin Trypsinogen Peptidase Enterokinase HCL Lecithin Lipase Nuclease

5. Hydrolysis “Adding Water” to a bond to break it Specifically, add an OH and an H to carbon an oxygen respectively “Reverse” of Dehydration Synthesis

6. “Enzyme”ProducedWhere it worksHow it worksSubstrateProduct Salivary amylaseSalivary glandsMouth, esophagus HydrolysisStarchMaltose Pancreatic amylase PancreasS.I.HydrolysisStarchMaltose MaltaseS.I HydrolysisMaltoseGlucose LactaseS.I. HydrolysisLactoseGlucose + galactose PepsinogenChief cells“no where” PepsinGastric reactionStomachBreaks peptide bonds (hydrolysis) Proteins- peptide bonds *hydrophobic a.a. Amino acids, smaller peptides TrypsinogenPancreasNone TrypsinActivated by enterokinase S.I.HydrolysisProteins (carboxyl of lysine and arginine) Amino acids, smaller peptides Peptidase/proteaseStomach, pancreas Stomach, S.I.HydrolysisProteinsAmino acids, smaller peptides

7. “Enzyme”ProducedWhere it worksHow it worksSubstrateProduct EnterokinaseDuodenumActivates trypsinogen HCLParietal cellStomachLow pHBacteria, enzymes, pepsinogen Dead things, pepsin LecithinLiverS.I.Emulsifies fats – amphiphilic FatsSmaller fat globules LipaseSaliva, pancreasMouth, S.I.HydrolysisFatsGlycerols and fatty acids NucleasePancreasS.I.Breaks “phosphate” bonds DNA, RANNucleic acids

8. http://www.namrata.co/

9. Now… Write out answer to Obj 8 After that, you should be able to write out an answer for Obj 10 when it comes up