1. Control # 2832 EE-27 T HE U NIVERSITY OF T EXAS H EALTH S CIENCE C ENTER AT H OUSTON MG Ramírez-Guzmán, AR Quiroz-Saavedra, H Ceja- Moreno, G Godoy-Brewer, E. Bofante, R Riascos.

2. The Authors have no disclosures in relation to this project.

3. PURPOSE Present a case 14 years old male patient presenting NMO and Hepatitis C, using this parameters as well as the imaging findings to establish the diagnosis that could guide future radiologists to make the differential diagnosis, and the satisfactory evolution using Rituximab as treatment.

4. A previously healthy 13 yr. male patient. Acute lumbar pain for 4 days with partial response to analgesics. Superior limbs weakness (0/5) + urinary incontinence, abolished osteotendinous reflexes, sensitive level on T10- T11, lack of a response and loss of the thermic sensibility. Guillain Barré syndrome diagnosis. Both parents have + serology for Hepatitis C virus (HCV). LP- Nl. Abnormal SSP on tibial nerve bilaterally, up to T12.

10. IMAGING FINDINGS Initial MRFollowing MR

11. IMAGING FINDINGS Initial MRFollowing MR

12. Ratelade J. Neuromyelitis optica: Aquaporin-4 based pathogenesis mechanisms and new therapies. Int J Biochem Cell Biol, 44 (9), 1519–1530 September 2013

13. SUMMARY Rare association between NMO and HCV has been reported. We present the first case to our knowledge of this assessment in a pediatric patient. MR helps the diagnosis and following of the patients with medullar lesions. Treatment with inmunomodulary medication showed clinical improvement. Radiologists must be aware of the changes associated with NMO in order to get an accurate diagnostic.

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