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: Acacia and Tragacanth

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1 : Acacia and Tragacanth
Pharmaceutical Aids : Acacia and Tragacanth

2 Objectives On completion of this topic, you would be able to:
The monograph of acacia and tragacanth

3 Acacia Synonyms : Gum Acacia, Gum Arabic..
Biological sources: Dried gummy exudation Obtained from the stem and branches of Acacia arabica wild belonging to family Leguminosae

4 Acacia Geographical Source : In India occurs in Punjab Rajasthan
Western Ghats Sri Lanka Africa Fig.64.1 Acacia plant

5 Acacia Description : Colour : Tears are Cream brown to red
Powder is light brown Odour : Odourless Taste : Bland &mucilaginous Size and shape : Irregular Solubility : Soluble in water Insoluble in alcohol

6 Acacia Standards: Moisture : Not more than15% Ash : 5 %
Chemical Constituents: • Arabin which is complex mixture of Calcium, Magnesium and Potassium salts of Arabic acid • On hydrolysis gives L-rhamnose, D-galactose, D- glucuronic acid Enzyme Oxydase

7 Acacia Identification Test :
Drug + Ruthenium red solution No pink colour 2. Aqua solution of gum acacia + 0.5ml hydrogen peroxide + 0.5ml of solution of Benzidine in alcohol Shake it well Blue colour

8 Acacia Uses : Storage : Demulcent Haemolysis when administered IV
Emulsifying and suspending agent Storage : Stored in well closed containers protected from light and in cool dry place

9 Tragacanth Synonym : Gum tragacanth, Tragacantha
Biological source : Dried gummy exudation obtained from incisions on stems and branches of Astragalus gummifer, Family : Leguminosae

10 Tragacanth Geographical Source : India Greece Iran Iraq Syria
Fig.63.2 Tragacanth plant

11 Tragacanth Organoleptic characters :
Colour : White or pale yellowish white Odour : OdourLess Taste : Taste less Size : 25 x 12 x 2 mm Shape : Thin, Flattened ribbon like flakes

12 Tragacanth Chemical Constituents :
Water soluble portion : 8to 10% Tragacanthin Water insoluble portion : Bassorin Traces of starch and Tragacanthic acid Galacturonic acid D-galactopyranose D-xylopyranose L-arabino-rhamnose

13 Tragacanth Chemical tests :
When warmed with sodium hydroxide solution, Canary yellow colour is developed With strong iodine solution, it gives Green colour

14 Tragacanth Uses : Demulcent Emollient in cosmetics Thickening agent
Suspending agent Binding agent

15 Summary In this class we learnt about :
Acacia is prepared from various species of Acacia arabica It is used as demulcent, emulsifying agent Tragacanth is prepared from various species of Astragalus It is used as demulcent, emulsifying agent, suspending agent, binding

16 Quiz Acacia obtained from Apis dorsata Arachis hypogea Acacia arabica
None of the above

17 Quiz 2. Acacia belongs to Leguminosae Apidae Solanaceae Graminae

18 Quiz 3.Tragacanth contains which of the following D-Galactose
D-Glucuronic acid D-Xylopyranose Linolein

19 Quiz 4. Tragacanth belongs to the family Euphorbiaceae Solanaceae
Leguminosae Umbelliferae

20 Frequently asked Questions
Write the uses and constituents of Acacia Write the monograph of acacia and Tragacanth What are Pharmaceutical aids. Give examples


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