1. The study of new reconstruction method
for Brain SPECT on dual detector system
사진 속도 느리게,,
Hyung Jin Lee

2. Brain spect procedure(1day protocol)
First source
acetazolamide
Basal acquisition
Second source
애니메이션 클릭하면서 설명
TST : 40~45min
Diamox acquisition

3. Brain SPECT Dual detector Short exam time Parallel collimator OSEM 2D
Triple detector
Short exam time
Fan-beam collimator
Spatial resolution
FBP-Metz filter
Optical contrast
FLASH 3D
Resolution
De-noise
Contrast
1day protocol
Metz filter: resolution recovery=contrast
2번째 사각형 컬러 변화,화살표 색깔 변환,.그물 빼고
Brain SPECT

4. Equivalent total exam time1
Equivalent total exam time 2
Setting acquisition parameter 3
Parallel collimator 4
New reconstruction method 5
Reasonable image quality

6. Hoffman 3D Brain Phantom
Specifications
- Cylinder inside diameter and height : 20.8 and 17.5 cm
100% bubble을 제거할 필요가 없는것은 머리안에 defect라고 가정하고 동일하게 acquire하였다.
- Fillable volume: ~ 1.2 liter
Source activity
- Basal/Diamox brain SPECT : 99mTc-HMPAO 15 mCi (15/30 mCi)
- 99mTc : mCi/L
(=15mCi*0.05/1.2L, 투여량의 5% 뇌조직에 분포를 가정함)

7. Experiment for Volunteer
99mTc-HMPAO : 15 mCi
Total count
1) Normal scan : 50 Kcounts/view (120 views : 6x106, 128 views : 6.4x106)
2) Short scan : 35 Kcounts/view (60% of Normal scan)
(120 views : 4.2x106, 128 views : 4.5x106)
Experiment summary
*TST : total scan time
Date
Scanner
Collimator
cps
Scan Time
Total Count
08/08
(pm 7:10)
ECAM 3
(Normal)
LEHR
1.5
32sec
TST : 34 min
5,931,948
08/12
(pm 8:00)
PRISM
Fan-beam (FB)
2.7
20sec
TST : 13.3 min
6,079,541
(pm 8:20)
(Short)
LEAP
2.3
15sec
TST : 16 min
4,116,391
08/22
(am 9:30)
1.8
TST : 21.3 min
4,699,939
*Unit : Kcount/sec (cps), sec/view (scan time)

8. *LEHR : low energy high resolution
Add Your Title
256% TST
Similar TC
PRISM-FB (Normal)
63% TST
79% TC
Add Your Title
ECAM3-LEHR (Normal)
32 sec/frame
(TST=34 min)
TC : 5.9×106 (5,931,948)
20 sec/frame
(TST=13.3 min)
TC : 6.1×106 (6,079,541)
Add Your Title
ECAM3-LEHR (Short)
20sec/frame
(TST=21.3 min)
TC : 4.7×106 (4,699,939)
75% TST
Similar TC
Add Your Title
ECAM3-LEAP (Short)
15sec/frame
(TST=16 min)
TC : 4.1×106 (4,116,391)
변화조건을 더 강조
*TST : total scan time
*FB : fan-beam collimator
*LEAP : low energy all purpose
*TC : total count
*LEHR : low energy high resolution

9. What is FLASH3D?
Flash 3D is an iterative reconstruction method for SPECT imaging with three dimensional resolution recovery and scatter correction
Benefits: They can be used to shorten SPECT and planar acquisition times, or to improve image quality.

10. Result Drawing ROI on 6 cold spheres and 4 background regions Contrast
To do…
Drawing ROI on 6 cold spheres and 4 background regions
Contrast
결과 그래프 애니메이션 효과로 삽입

11. Result Drawing ROI on 4 hot spheres and 3 background regions
To do…
Drawing ROI on 4 hot spheres and 3 background regions
SNR=lesion average divided by background standard deviation
Sphere
S/R

12. Result

13. PRISM3000 vs ECAM
(Hoffman 3D Phantom)

14. Hoffman-3D 비교 PRISM-FB-30sec *FBP-METZ ECAM-LEHR-15sec *FLASH3D-S8I8
**GAUSS-7mm
토탈 검사스캔타임 쓰고 이미지 강조,
ECAM-LEHR-25sec
*FLASH3D-S8I8
**GAUSS-7mm

15. Subset8에 iteration 변화 이미지(FLASH3D)
Non-filter
OSEM2D 이미지 삽입(노말로)
Post-filtering Gaussian 5mm

16. PRISM3000 vs ECAM
(Volunteer image)

17. Why it has to be 20sec! Diamox 1day protocol Tc-99m dosage
15~20sec/frame
Tc-99m dosage
기준카운터 즉 50,000카운터 의 65~70%
65~70% raw data

18. Result
e.Cam fbp/osem/flash

19. Result E.cam/LEAP/15sec/FLASH3D E.cam/LEHR/20sec/FLASH3D
이미지 배경화면 다시,,,택스트 상자 편집 및 글자 색깔 강조 콜리메이터
E.Cam/LEUHR/20sec
FLASH3D

20. Result PRISM/Fan/20SEC/METZ E.cam/LEAP/15sec/FLASH3D
E.cam/LEHR/32sec/FLASH3D
8/8/5…마지막 20SEC 영상을 강조하게 테두리 효과
E.camLEHR/20sec/FLASH3D

21. Conclusion

22. Thank You !