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AP Biology DNA Structure & Replication
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Nucleic Acid Structure
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Complimentary Base Pairing
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S Phase of Cell Cycle
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Theta Replication in Prokaryotes Origin of replication Replication fork Termination of replication
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Linear Replication in Eukaryotes
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. The parent molecule has two complementary strands of DNA. Each base is paired by hydrogen bonding with its specific partner, A with T and G with C.
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. The parent molecule has two complementary strands of DNA. Each base is paired by hydrogen bonding with its specific partner, A with T and G with C. The first step in replication is separation of the two DNA strands.
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Semi Conservative process of DNA Replication The parent molecule has two complementary strands of DNA. Each base is paired by hydrogen bonding with its specific partner, A with T and G with C. The first step in replication is separation of the two DNA strands. Each parental strand now serves as a template that determines the order of nucleotides along a new, complementary strand.
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Origins and Replication bubbles
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DNA Replication
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DNA Replication by adding Nucleosides on the 3’ end New strand 5 end Phosphate Base Sugar Template strand 3 end 5 end 3 end 5 end 3 end 5 end 3 end Nucleoside triphosphate DNA polymerase Pyrophosphate
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5 Carbon Sugar Important Parts (It could be DNA or RNA)
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Helicase is the GREEN “blob”
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RNA Primer (Remember, RNA is temporary)
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. New strand 5 end Phosphate Base Sugar Template strand 3 end 5 end 3 end 5 end 3 end 5 end 3 end Nucleoside triphosphate DNA polymerase Pyrophosphate
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Nucleotide Excision Repair
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Telomere Removal at the Chromosome Ends End of parental DNA strands 5 3 Lagging strand 5 3 Last fragment RNA primer Leading strand Lagging strand Previous fragment Primer removed but cannot be replaced with DNA because no 3 end available for DNA polymerase 5 3 Removal of primers and replacement with DNA where a 3 end is available Second round of replication 5 3 5 3 Further rounds of replication New leading strand Shorter and shorter daughter molecules
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Apoptosis in the hand
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