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REVISION
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يمكن الاستفادة من هذا العرض التقديمي في مراجعة ما يتعلق ب WBCs maturation & Leukemia
هذا الجزء لا يشمل RBCs يمكن المراجعة ذاتيا عن طريق الضغط على زر العرض بحيث ستظهر الصورة بدون تعريف, وعلى الطالبة محاولة التعرف عليها وعند النقر على الماوس سيظهر تعريف الصورة.
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DIFFERENT MYELOID STAGES
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Charecteristics of granulocyte granules
Charecteristics of granulocyte granules. The colour of the letters is the same as that of the granules and the backgroung the colour of cytoplasm of the cell the granules are most prominant in.
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Pronormoblast
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Auer rods in promyelocytes of M3
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Toxic granulation of neutrophil
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orthochromic normoblast
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A- Pronormoblast B- polychromatic normoblast C- orthochromic normoblast
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Promonocytes (with a single fissure in the nucleus)
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b a A- neutrophilic metamyelocyte b- neutrophilic myelocyte
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Promonocytes (with a single fissure in the nucleus)
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b b c a A- Promonocyte B- orthochromic normoblast c- band neutrophil
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Peroxidase negative , PAS positive blast cells
cells of the different populations, lymphoblasts from L2 type
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basophilicnormoblasts
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b b b b c b a a b d b f e A-pronormoblast b- orthochromic normoblast C- neutrophilic myelocyte D- neutrophilic metamyelocyte E- band neutrophil F- segmented neutrophil
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b a a a a b b A- Promonocyte B- myeloid cell
(both are present in M4 leukemia b
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a b b a- polychromatic normoblast (megaloblast)
b- orthochromic normoblast
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a b b a A- Promonocyte B- promyelocyte (M4 leukemia)
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Different maturation stages of myeloid cell in M2 leukemia.
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Pronormoblast
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Different maturation stages of myeloid cell with M2 leukemia.
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Myeloblasts from M1 or M0 Peroxidase will confirm diagnosis
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Myeloblasts from M1 Auer rods confirm diagnosis of M1 not present in M0
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basophilic myelocyte
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Peroxidase negative , PAS positive blast cells
Small cells of the same population, lymphoblasts from L1 type
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Peroxidase negative , PAS positive blast cells
Small cells of the same population, lymphoblasts from L1 type
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Peroxidase negative , PAS positive blast cells
cells of the different populations, lymphoblasts from L2 type
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Monocytic precursors of M5 leukemia
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Lymphoblasts of hairy cell leukemia (myelofibrosis)
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Lymphoblasts of hairy cell leukemia (myelofibrosis)
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Lymphoblasts of hairy cell leukemia (myelofibrosis)
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Plasma cells of multiple myeloma (note the multinucleated cell)
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PAS +ve lymphoblast from L3 leukemia
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Plasma cells of multiple myeloma (note the multinucleated cell)
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Plasma cells of multiple myeloma (note the multinucleated cell)
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Peroxidase negative , PAS positive blast cells
cells of the different populations, lymphoblasts from L2 type
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Erythrophagocytosis
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Erythrophagocytosis
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LE cell
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a c b e d d d d A- Eosinophilic myelocyte B- Promyelocyte
C- Basophilic normoblast D- Polychromayic normoblast E- Orthochromic normoblast
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Eosinophilic myelocyte
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Basophilic metamyelocyte
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Lymphoblasts of hairy cell leukemia (myelofibrosis)
The red stain is ACP +ve hairy cell
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Eosinophilic metamyelocyte
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megakaryocyte
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Segmented Basophil
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Promyelocytes with auer rod bundles from M3
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CD 41 +ve cells Megakaryoblast from M7 leukemia
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megakaryoblast
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pronormoblasts
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Erythroid prcusors from M6 Leukemia
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MPO stain Myeloblast from M1
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Different myeloid stages from M2
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Different myeloid stages from M2
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Different myeloid stages from M2
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Promyelocytes with auer rod bundles from M3
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Different eythroid precursors in M6 leukemia
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Non specific esterase +ve cells
Monoblast From M5
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PAS +ve lymphoblast from L1 leukemia
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neutrophilic metamyelocyte and segmented neutrophil
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