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Study design: a randomized placebo- controlled crossover trial of 2 periods of 4 weeks Nicole A.J. van der Linde, et al. Hypertension 2006;47;1125-1130.

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Presentation on theme: "Study design: a randomized placebo- controlled crossover trial of 2 periods of 4 weeks Nicole A.J. van der Linde, et al. Hypertension 2006;47;1125-1130."— Presentation transcript:

1 Study design: a randomized placebo- controlled crossover trial of 2 periods of 4 weeks Nicole A.J. van der Linde, et al. Hypertension 2006;47;1125-1130

2 Values of Lipids and Baseline Hemodynamics Before Infusion of Ang II and Norepinephrine After 4 Weeks of Placebo or Treatment With Fluvastatin Nicole A.J. van der Linde, et al. Hypertension 2006;47;1125-1130

3 Mean Differences of Changes in Systolic and Diastolic Blood Pressure During Infusion of Ang II and Norepinephrine at 4 Weeks of Placebo or Fluvastatin Nicole A.J. van der Linde, et al. Hypertension 2006;47;1125-1130

4 Bar graphs showing responses of systolic and diastolic blood pressure to increasing infusion rates of Ang II and norepinephrine (Nor) Open and light grey bar responses after 4 weeks of placebo; black and dark gray bars responses after 4 weeks of fluvastatin Nicole A.J. van der Linde, et al. Hypertension 2006;47;1125-1130

5 Values of infusion rates of Ang II and Norepinephrine (Nor) at Pd-20 after 4 weeks of placebo and fluvastatin Paired t test was used for statistical analysis Nicole A.J. van der Linde, et al. Hypertension 2006;47;1125-1130

6 Concentrations of Plasma Ang II and Norepinephrine at Baseline and During Infusion of Ang II or Norepinephrine and Plasma Renin Activity at Baseline Nicole A.J. van der Linde, et al. Hypertension 2006;47;1125-1130


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