Presentation is loading. Please wait.

Presentation is loading. Please wait.

Date of download: 6/23/2016 Copyright © The American College of Cardiology. All rights reserved. From: Loss of Cardiac Magnesium in Experimental Heart.

Similar presentations


Presentation on theme: "Date of download: 6/23/2016 Copyright © The American College of Cardiology. All rights reserved. From: Loss of Cardiac Magnesium in Experimental Heart."— Presentation transcript:

1 Date of download: 6/23/2016 Copyright © The American College of Cardiology. All rights reserved. From: Loss of Cardiac Magnesium in Experimental Heart Failure Prolongs and Destabilizes Repolarization in Dogs J Am Coll Cardiol. 1998;31(3):701-706. doi:10.1016/S0735-1097(97)00524-X Total cellular magnesium measured in the sublingual epithelium from six dogs before and after 3 weeks of ventricular pacing at 240 beats/min (p < 0.01). Figure Legend:

2 Date of download: 6/23/2016 Copyright © The American College of Cardiology. All rights reserved. From: Loss of Cardiac Magnesium in Experimental Heart Failure Prolongs and Destabilizes Repolarization in Dogs J Am Coll Cardiol. 1998;31(3):701-706. doi:10.1016/S0735-1097(97)00524-X Intracellular, ionized magnesium in 100 cells from eight normal dogs compared with [Mg 2+ ] i in 98 cardiac myocytes from eight dogs with congestive heart failure (CHF) (mean value ± SEM, p < 0.00001). Figure Legend:

3 Date of download: 6/23/2016 Copyright © The American College of Cardiology. All rights reserved. From: Loss of Cardiac Magnesium in Experimental Heart Failure Prolongs and Destabilizes Repolarization in Dogs J Am Coll Cardiol. 1998;31(3):701-706. doi:10.1016/S0735-1097(97)00524-X Comparison of the mean [Mg 2+ ] i concentration in cardiac myocytes from eight control dogs and eight dogs with congestive heart failure (CHF) (p < 0.003). Figure Legend:

4 Date of download: 6/23/2016 Copyright © The American College of Cardiology. All rights reserved. From: Loss of Cardiac Magnesium in Experimental Heart Failure Prolongs and Destabilizes Repolarization in Dogs J Am Coll Cardiol. 1998;31(3):701-706. doi:10.1016/S0735-1097(97)00524-X The effect of dialysis on the rest membrane potential (open bars), APD 50 (solid bars) and APD 90 (hatched bars) in cardiac myocytes. ∗ p < 0.05, ∗∗ p < 0.01, ∗∗∗ p < 0.001 versus before dialysis. A, Dialysis with 1.0 mmol/liter MgCl 2 in five myocytes with heart failure. B, Dialysis with 0.5 mmol/liter MgCl 2 in five myocytes with heart failure. C, Dialysis with 1.0 mmol/liter MgCl 2 in six control myocytes. D, Dialysis with 0.5 mmol/liter MgCl 2 in six control myocytes. Figure Legend:

5 Date of download: 6/23/2016 Copyright © The American College of Cardiology. All rights reserved. From: Loss of Cardiac Magnesium in Experimental Heart Failure Prolongs and Destabilizes Repolarization in Dogs J Am Coll Cardiol. 1998;31(3):701-706. doi:10.1016/S0735-1097(97)00524-X Superimposition of a representative AP from a failing myocyte before and after dialysis with a pipette buffer containing 1.0 mmol/liter MgCl 2. Figure Legend:

6 Date of download: 6/23/2016 Copyright © The American College of Cardiology. All rights reserved. From: Loss of Cardiac Magnesium in Experimental Heart Failure Prolongs and Destabilizes Repolarization in Dogs J Am Coll Cardiol. 1998;31(3):701-706. doi:10.1016/S0735-1097(97)00524-X A, Fifty consecutive APs from a failing myocyte stimulated at 1 Hz at 25°C. B, Fifty consecutive APs from the same cell after dialysis with a pipette buffer containing 1.0 mmol/liter MgCl 2. Figure Legend:


Download ppt "Date of download: 6/23/2016 Copyright © The American College of Cardiology. All rights reserved. From: Loss of Cardiac Magnesium in Experimental Heart."

Similar presentations


Ads by Google