1. VIRUSES Ebola virus Ebola virus particles, colored digitally, emerging from a type of monkey epithelial cell line

2. HW: – Read Text 18.2 pg. 525-531 – Take notes under the four main headings – Answer Questions 1-3 on page 531 WHAT ARE THE VIRUSES YOU HAVE HEARD OF?

3. Resources NPR: Viruses Attack Discovery News: Are Viruses Alive?Are Viruses Alive? EC: Virus Evolution (10 points possible – See Website)Virus Evolution Bozeman Science: Viruses (9 min.)Viruses KHAN Academy: VirusesViruses Amoeba Sisters: Viruses (7 Min.)Viruses

4. Outline Anatomy of a Virus Are viruses alive? Common Viral Diseases Viral Replication – Lytic – Lysogenic Retroviruses

5. What is a virus? A non-living strand of genetic material within a protein coat Size?

7. Anatomy of a Virus

8. Glycoproteins?

9. Are Viruses Alive? Characteristics of living things? – List them. DiscoveryNews: Are Viruses Alive?Are Viruses Alive?

10. Viral Shapes Special thanks to Dr. Dennis Kunkel www.denniskunkel.com

11. 4 Basic Shapes Helical Polyhedral Spherical Bacteriophage

12. Helical Resemble Long Rods Flexible or rigid Examples – TMV – Ebola – Rabies Tobacco Mosaic Virus

13. Helical Viruses cont. Tobacco Mosaic Virus

14. Polyhedral Polyhedral means many sided 3-D shape Most are iscosahedrons Examples – Adenovirus – Polio virus – Common cold – Hepatitis Adenovirus

15. Polyhedral cont. Polio Virus Pappilomavirus

16. Spherical Also called “enveloped” viruses Roughly spherical Protein coat and DNA/RNA covered by an membrane envelope Influenza Virus

17. More Spherical Viruses Herpes Simplex Virus

18. A Deadly Sphere Human Immunodeficiency Virus

19. HIV

20. Bacteriophage Most complex viruses Infect bacteria Consist of: – Capsid (head) DNA inside – Tail – Tail Plate – Tail fibers (legs)

22. Common Viral Diseases Measles… Immune Response. Should you Vaccine or not?

23. Viral Infection  Viral Replication Lytic Cycle & Lysogenic Cycle NPR: Viruses Attack

26. I'm a Virus! (Mr. W's Virus Rap) Virus Rap What are the differences between lysogenic and lytic cycles of Virus Replication?

27. Retro Virus

28. How they really look…

30. SMART-Starters What are two aspects of a VIRUS that are similar to living things? What are two aspects of a VIRUS that are similar to non-living things?

31. SMART-Starters What is difference between an HIV virus and a bacteriophage? Possible differences: size? shape? target host? other?