1. URINARY SYSTEM

2. Functions Excretion – removal of organic waste products from body fluids Elimination – discharge of these waste products into environment Maintains normal volume and solute concentration of blood plasma

3. 4 Major Components Kidney Ureter Bladder Urethra

4. Kidneys Filter waste from blood Reabsorb substances the body requires

6. Anatomy of the Kidney Cortex is the outer portion Medulla is the inner portion Calyces give urine to renal pelvis

7. Pathway of Blood in the Kidney

8. Nephrons Structural and functional unit of kidney A kidney contains about 1 million nephrons

9. Bowman’s capsule – double-walled sac which surrounds the glomerulus Glomerulus – cluster of capillaries; filters out substances from blood - water, salt, waste

10. Osmosis in the Loop of Henle allows our kidney to maintain proper water concentration: waste products to pass into the bloodstream; water and salt are reabsorbed at the same time Loop of Henle

12. Ureters Slender tubes Runs from the hilus of kidney to posterior aspect of bladder Passageways that carry urine Peristalsis helps the ureters to propel urine to bladder

13. Bladder Smooth, collapsible muscular sac that stretches as it fills with urine A moderately full bladder holds about 1 pint/500 ml of urine, but is capable of holding more than twice that amount.

14. Urethra Thin-walled tube that carries urine by peristalsis from the bladder to the outside of the body Sphincters Internal urethral sphincter- involuntary sphincter that keeps the urethra closed when urine is not being passed; at the bladder-urethra junction External urethral sphincter- voluntary sphincter made of skeletal muscle

15. Control of blood composition by the kidneys Urine Contains Water & Urea (the main contributor of Nitrogenous waste)

16. Maintaining balance Water accounts for about 60% (give or take) of body weight The average adult takes in about 2 ½ quarts of water a day (half from food) Water is lost through urine, fecal matter, expiration & perspiration

17. ADH Antidiuretic hormone (ADH)- functions to conserve water output into urine Low water intake=more ADH=less urine excreted High water intake=low ADH= more urine excreted Alcohol prevents release of ADH causing low water reabsorption and increased urine production.

18. Common Diuretics Alcohol Caffeine Pregnancy Diabetes

19. Urination Process of releasing urine through the urethra Ordinarily, the bladder collects urine until about 200 ml have accumulated. The stretching of the bladder activates stretch receptors, leading to reflex contractions.

20. Contractions become stronger, forcing stored urine past the internal sphincter into the upper part of the urethra. Now the person feels the urge to urinate. The lower external sphincter can be voluntarily controlled. Bladder emptying can be postponed if desired, causing the reflex contractions to stop within a minute or so. If convenient, the external sphincter can be relaxed so that urine is flushed form the body. But eventually, urination will occur whether one wills it or not.

21. Kidney Stones Salts and calcium found in concentrated urine can crystallize to become a stone Causes pain and reduces or prevents filtration in the affected kidney

22. Closure What is the function of the Kidneys? Describe the loop of Henle include regions that are hypertonic and hypotonic. (include bowman’s capsule, descending loop, ascending loop and collecting duct) Give a situation in which your body would have low ADH. Give a situation in which your body would have high ADH. Why is it important to maintain of your bodies osmotic pressure?