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Gregor Mendel.  Inheritance  An individual’s characteristics are determined by factors that are passed from one parental generation to the next.  The.

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Presentation on theme: "Gregor Mendel.  Inheritance  An individual’s characteristics are determined by factors that are passed from one parental generation to the next.  The."— Presentation transcript:

1 Gregor Mendel

2  Inheritance  An individual’s characteristics are determined by factors that are passed from one parental generation to the next.  The delivery of characteristics from parent to offspring is called heredity.

3  Genetics  The scientific study of heredity, known as genetics, is the key to understanding what makes each organism unique.

4  Experiments of Gregor Mendel  Mendel carried out his work with ordinary garden peas, partly because:  Peas are small and easy to grow  A single pea plant can produce hundreds of offspring  Observable characteristics

5  Fertilization  A trait is a specific characteristic of an individual, such as seed color or plant height, and may vary from one individual to another.

6   Mendel decided to “cross” his stocks of true-breeding plants—he caused one plant to reproduce with another plant. Fertilization

7  Hybrids  Mendel crossed plants with each of the seven contrasting characteristics and then studied their offspring.  The offspring of crosses between parents with different traits are called hybrids.

8   When doing genetic crosses, we call the original pair of plants the P, or parental, generation. Genes & Alleles

9   Their offspring are called the F 1, or “first filial,” generation. Genes & Alleles

10   For each trait studied in Mendel’s experiments, all the offspring had the characteristics of only one of their parents, as shown in the table.  In each cross, the nature of the other parent, with regard to each trait, seemed to have disappeared. Genes & Alleles

11   From his experiments, Mendel drew two conclusions:  An individual’s characteristics are determined by factors that are passed from one parental generation to the next.  Scientists call the factors that are passed from parent to offspring genes.

12  Genes & Alleles  Each of the traits Mendel studied was controlled by one gene that occurred in two contrasting varieties.  These gene variations produced different expressions, or forms, of each trait.  The different forms of a gene are called alleles.

13  Dominant & Recessive Traits  Mendel’s second conclusion is called the principle of dominance.  This principle states that some alleles are dominant and others are recessive.

14   In Mendel’s experiments, the allele for tall plants was dominant and the allele for short plants was recessive. Dominant Traits

15  Segregation  During gamete formation, the alleles for each gene segregate from each other, so that each gamete carries only one allele for each gene.

16  Segregation  Mendel wanted to find out what had happened to the recessive alleles.  To find out, Mendel allowed all seven kinds of F 1 hybrids to self- pollinate. The offspring of an F 1 cross are called the F 2 generation.  The F 2 offspring of Mendel’s experiment are shown.

17  Segregation  When Mendel compared the F 2 plants, he discovered the traits controlled by the recessive alleles reappeared in the second generation.  Roughly one fourth of the F 2 plants showed the trait controlled by the recessive allele.

18  Segregation  Mendel assumed that a dominant allele had masked the corresponding recessive allele in the F 1 generation.  The reappearance of the recessive trait in the F 2 generation indicated that, at some point, the allele for shortness had separated from the allele for tallness.

19  Probability and Genetics  Punnett squares use mathematical probability to help predict the genotype and phenotype combinations in genetic crosses.

20  Probability & Genetics  Probability is the likelihood that a particular event will occur.  There are two possible outcomes of a coin flip: The coin may land either heads up or tails up.  The chance, or probability, of either outcome is equal. Therefore, the probability that a single coin flip will land heads up is 1 chance in 2. This amounts to 1/2, or 50 percent.

21  Consider a couple examples: If you flip a coin once in the air, what is the chance that you will get a tails? If you flipped the coin again, what are the chances of getting tails again? Probability Cont.

22  Probability cont’  Although we can use probability to predict future traits in offspring, the numbers do not always work out in reality.  Consider an example: If you flip a coin once in the air, what is the chance that you will get a tails? If you flipped the coin again, what are the chances of getting tails again?

23  Probability cont’  Now consider this example:  What are the chances of flipping tails three times in a row?

24  Probability cont’ What are the chances of flipping tails three times in a row? ½ x ½ x ½ = 1/8 Remember, each coin flip is an independent event with a ½ probability of landing tails up each time.

25  Probability Rules If “x AND y will happen”  Then multiply the probability of x by the probability of y  (probability of x)*(probability of y)

26  Probability Example  What are your chances of rolling a 1 twice in a row on a normal die?  1/6 * 1/6 = 1/36 chance

27  Your Turn  What is your chance of rolling a 5 the first time you roll a die and a 6 the second time? A)1/6B) 1/36 C) 1/3D) 1/4

28  Answer  What are the chances of rolling a 5 the first time you roll a die and a 6 the second time you roll?  You multiply your chances –  1/6 * 1/6 = 1/36

29  More Probability Rules If “x OR y will happen”  Then add the probability of x to the probability of y  (probability of x) + (probability of y)

30  Example What is your chance of rolling a 1 or a 6 the first time you roll a die?  1/6 + 1/6 = 2/6 or 1/3

31  Your Turn  What is your chance of rolling a 1, a 3, or a 6 the first time you roll a die? A) 1/6 B) 1/36 C) 1/2D) 1/4

32  Answer  What is your chance of rolling a 1, a 3, or a 6 the first time you roll a die?  1/6 + 1/6 + 1/6 = 3/6 or 1/2

33  Advanced Question  What is your chance of rolling a 1 or 2 twice in a row? A) 1/3B) 1/2 C) 1/6D) 1/9

34  Answer  What is your chance of rolling a 1 or 2 twice in a row?  1/6 +1/6 = 2/6 or 1/3 – first roll  1/6 +1/6 = 2/6 or 1/3 – second roll  1/3 * 1/3 = 1/9

35  Probability cont’ What does this mean!? Past outcomes do not affect the future! Just because you flipped a tails before, does not mean you will next time. Independent events will have the same probability as others, but when there are more than one trait we are testing for, there are more possible outcomes.

36  Probability cont’  The way in which alleles segregate during gamete formation is every bit as random as a coin flip or a dice roll.  Therefore, the principles of probability can be used to predict the outcomes of genetic crosses.

37  Probability cont’  Probabilities predict the average outcome of a large number of events.  The larger the numbe r of offspring, the closer the results will be to the predicted values.  If an F 2 generation contains just three or four offspring, it may not match Mendel’s ratios.  When an F 2 generation contains hundreds or thousands of individuals, the ratios usually come very close to matching Mendel’s predictions

38  Genotype & Phenotype  Genotype – genetic makeup  Ex: Tt  Phenotype – physical traits  Tall plant or short plant

39  Homozygous & Heterozygous  Organisms that have two identical alleles for a particular gene—TT or tt in this example—are said to be homozygous.

40  Homozygous & Heterozygous  Organisms that have two different alleles for the same gene—such as Tt— are heterozygous.

41  Predicting Phenotypes TT tTt t  Using Punnett Squares  Cross true-breeding strains.  Genotype – 100% Tt  Phenotype – 100% tall

42  Predicting Phenotypes Tt TTTTt t tt  Using Punnett Squares  Cross F 1 generation  Genotype – 25% TT - 50% Tt - 25% tt  Genotypic ratio – 1:2:1  Phenotype – 75% - tall - 25% - short  Phenotypic ratio- 3:1

43  Summary of Mendel  The inheritance of biological characteristics is determined by individual units called genes, which are passed from parents to offspring.

44   Where two or more forms (alleles) of the gene for a single trait exist, some forms of the gene may be dominant and others may be recessive. Summary of Mendel

45   In most sexually reproducing organisms, each adult has two copies of each gene—one from each parent. These genes segregate from each other when gametes are formed.


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