1. Kidney and Nephron Structure

3. Major Functions of the Kidney Regulation of body fluid Regulating concentrations of electrolytes (Na+, K+, Mg+, etc) Regulation of acid-base balance Clearance of metabolic waste products (urea, uric acid, creatinine)

4. Anatomy of the Kidney Cortex Medulla outer medulla inner medulla Papilla Minor calyx Major calyx Renal pelvis

5. nephron—functional unit of the kidney Found in cortex and medulla Regulates water concentration Filters blood Reabsorbs necessary ions and substances Creates urine Kidney Animation

6. Nephron Anatomy Bowman’s capsule Glomerulus Proximal convoluted tubule Distal convoluted tubule

9. Sources: UNCC Bioweb [Internet]. 2010. Charlotte, NC. [updated Jun 2010; accessed Jun 2010]. Available from: www.bioweb.uncc.eduwww.bioweb.uncc.edu