1. Point of Care Coagulation Testing in Europe
Shree Viswadia
London, 9th December’ 2003
© 2003 Frost & Sullivan. All rights reserved. This document contains highly confidential information and is the sole property of Frost & Sullivan. No part of it may be circulated, quoted, copied or otherwise reproduced without the written approval of Frost & Sullivan.

2. Agenda Introduction Agenda Overview of the Market Key Market Trends
Market Size
Key Market Forecasts
Regional Trends
Competitive Landscape
Addressing the Challenges
Take Home Comments
Q & A

3. Overview of the Market Point of Care Testing 38.9% 5.2% 4.7%
Self Testing
4.7%
GP Based Testing
Hospital POC Testing
Lab Based Testing
61.1%
90.1%
Note: All figures are rounded. Source: Frost & Sullivan

4. Key Market Trends POC in emergency and critical care
Test Menus
Connectivity
Marketing & Distribution Agreements
Laboratory Testing
Sample Sizes
Lack of Legislation
POC Test Prices

5. Revenue (Euro million)
Market Size
400 25
350 20
300
250 15
Revenue (Euro million)
Growth Rate (%)
200 10
150
100 5 50
1999
2000
2001
2002
2003
2004
2005
2006
2007
2008
2009
Year

6. Key Market Forecasts Point of Care Testing: CAGR 18%
Source: Frost & Sullivan
Point of Care Testing: CAGR 18%
Near Patient Testing:
CAGR 17.6%
Self Testing:
CAGR 6%
2003
2009
Enoxaparin Card Launched
Ximelagatran launched
Reimbursement issues resolved
Other DTI’s launched (GSK, Boehringer)
DNA based testing

7. Market Potential 2003
650,000
Germany
France UK
Italy
Spain
Benelux
Scandinavia
Alps
270,000
170,000
172,000
64,000
750,000
520,000
600,000
Note: All figures are rounded. Source: Frost & Sullivan

8. Regional Trends Key Laboratory based Testing Near Patient Testing
Self Testing
Not included in Study
Source: Frost & Sullivan

9. Competitive Landscape
Whole Blood Analysers
TEG
ROTEM
Other
Self Testing Analysers
Coaguchek S
Protime
INRatio
Near Patient Testing Analysers
Thrombotest
Rapidpoint
GEM
I-Stat PCA
Hemachron
ACT III
Automated
Coaguchek
Pro/ DM
Sonoclot
PFA 100
Source: Frost & Sullivan

10. Addressing the Challenges
Challenges in Quality Control
Home monitor results inconsistent with traditional laboratory results
Attitudes of the Physicians as gatekeepers
Reimbursement Schedules are inconsistent
Development of Thrombin Inhibitor Drugs has potential of reducing customer base

11. Take-Home Comments
Coagulation Testing steadily moving away from Traditional Testing
POC coagulation testing market growing at CAGR 17.6% in Europe
Opportunities

12. Thank you - Any Questions?
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