1. Department of ORL-HNS, Kyung Hee Univ., Seoul, Korea Sponsor: The Korean Rhinologic Society Allergic Rhinitis : What ’ s News in Clinic & Basic Science November 9 – 11, 2007

2. Invitation Dear Colleagues, It gives me a great pleasure to invite you on behalf of faculty in our department to the Kyunghee International Rhinologic Symposium (KIRS) 2007. This symposium is annual meeting for basic science and clinical aspects of rhinologic fields focused on allergic rhinitis, sinusitis and polyp, and obstructive sleep apnea. In this year, symposium will be focused on allergic rhinitis. Session will cover pediatric allergic rhinitis, comorbidity, immunotherapy, chronic cough, occupational rhinitis and hygiene, etc. A variety of topics will be dealt with part of basic science, consisting of stem cell, gene anomaly, various cytokines and superantigens. Main conference will be held from Nov 10 to 11. Before the main conference (Nov. 9) there will be an observation program of live rhinologic surgery (endoscopic sinus surgery, multilevel sleep surgery and various kind of rhinoplasty) from only limited number of participants. We believe this conference provides a forum to discuss and to exchange experiences in the interest of providing the best possible care for patients. We look forward to welcoming you in November. Joong Saeng Cho

3. Live Surgery Schedules : Operating Room at Kyung Hee Medical Center 9th Nov. (Friday) AM Endoscpic Surgery (Joong Saeng Cho, Kun Hee Lee) - Endoscopic Sinus Surgery - Endoscopic Septal Surgery PM Sleep Apnea Surgery (Sung Wan Kim / Young Gyu Eun) - Palatal and Tongue base Surgery 10th Nov. (Saturday) AM Septorhinoplasty Surgery (Kun Hee Lee / Seung Youp Shin)

4. Lecture Schedules : Kyung Hee Medical Center Seminar Room 10th Nov. (Saturday) 12:30 – 13:00 Registration 13:00 – 14:10 Opening Remark Session I 13:10 – 13:40 Allergy and Mucin Secretion in Upper Airway Mucosa Jens Ponikau 13:40 - 14:10 Immunologic Role of Nasal Epithelial Cells Seung Heon Shin 14:10 – 14:40 Goblet cells and Allergic Inflammation in Rat Nasal Epithelium Takeshi Shimizu 14:40 – 15:10 Detection of specific IgE antibody in nasal mucosa and secretion at nasal mucosal allergy in the absence of systemic allergy. Jong Cheol Choi 15:10 – 15:30 Coffee Break Session II 15:30 - 16:00 Effect of (-)-epigallocatechin-3-gallate on TGFβ1-stimulated Collagen Expression in Nasal Polyp Fibroblasts Hee Joon Kang 16:00 – 16:30 Role of Prostaglandins (especially synthases and receptors) and Costimulatory Molecules in The Pathophysiology of Allergic Rhinitis Mitsuhiro Okano 16:30 - 17:00 The Role of Worm Infestation in Allergic Rhinitis Kuljit Singh 17:00 - 17:30 Minimal persistent inflammation in Allergic rhinitis Dong Zhen 17:30 - 18:00 3-hydroxyanthranilic and inhibits PDK1 activation and suppresses Experimental asthma by inducing T cell apoptosis Ji Hun Mo

5. 11th Nov. (Sunday) 08:30 – 09:00 Registration 09:00 – 09:10 Opening Remark Session III 09:10 – 09:40 Nasal Steroids: How Do They Work in Chronic Rhinosinusitis Jens Ponikau 09:40 – 10:10 Functional Roles of Nitric Oxide in The Inflammatory Responses in Human Nose and Paranasal Sinuses Sachio Takeno 10:10 – 10:40 Stem Cell and Allergic Rhinitis: Immunomodulatory Effects of ADSC in Allergic Rhinitis Mouse Model Hwan Jung Roh 10:40 – 11:00 Coffee Break Session IV 11:00 – 11:30 Quality of Life in Patients with Allergic Rhinitis Kun Hee Lee 11:30 – 12:00 Differences in Allergic Rhinitis Between Adults and Children Joong Saeng Cho 12:00 – 12:30 Allergic Rhinitis and Asthma: Similarities & Differences Yeong Ho Rha 12:30 – 13:30 Lunch Session V 13:30 – 14:00 Allergic Inflammation in Adenoid Tissue Seung Youp Shin 14:00 – 14:30 Allergic Rhinitis and Sleep Apnea Soo Kweon Koo 14:30 – 15:00 Coffee Break Session VI 15:00 – 15:30 Immunostimulatory DNA in the treatment of Allergic Rhinitis Tae Bin Won 15:30 – 16:00 The Genetic Effect of Allergen Immunotherapy in Asthmatic Patients Gyu Young Hur 16:00 – 16:30 Sublingual immunotherapy for allergic rhinitis Dong Young Kim 16:30 Closing Remark

6. Congress Information 1. Venue Lecture Hall of Information & Administration Building in Kyung Hee Medical Center 2. Registration Delegate full scope : 70,000 KRW(until 11/5) 80,000 KRW(after 11/5) lecture only : 40,000 KRW(until 11/5) 50,000 KRW(after 11/5) Trainee full scope : 50,000 KRW(until 11/5) 60,000 KRW(after 11/5) lecture only : 30,000 KRW(until 11/5) 40,000 KRW(after 11/5) * Number of full scope participants will be limited less than 20. 3. Bank transfer Bank Name : HANABANK Account No. : 257-910129-00407 (Sung Wan Kim) Swift Code : HNBNKRSE Bank Address : (130-050) 1-1 Hoegi- Dong, Dongdaemun-Gu, Seoul, Korea 4. Contact Information E-mail: khuent@khu.ac.kr Tel: 82-2-958-8474, Fax.: 82-2-958-8470 5. Registration Form Name Delegate ( ) or Trainee ( ) Institute License No. Phone No. E-mail