1. Date of download: 6/25/2016 Copyright © The American College of Cardiology. All rights reserved. From: The CardioMetabolic Health Alliance: Working Toward a New Care Model for the Metabolic Syndrome J Am Coll Cardiol. 2015;66(9):1050-1067. doi:10.1016/j.jacc.2015.06.1328 Paradigm for Subtyping MetS Substantial variability in end-organ consequences related to MetS underscores a need to identify subtypes of MetS on the basis of pathophysiology that can be targeted for specific evidence-based management strategies. ASCVD = atherosclerotic cardiovascular disease; MetS = metabolic syndrome. Figure Legend:

2. Date of download: 6/25/2016 Copyright © The American College of Cardiology. All rights reserved. From: The CardioMetabolic Health Alliance: Working Toward a New Care Model for the Metabolic Syndrome J Am Coll Cardiol. 2015;66(9):1050-1067. doi:10.1016/j.jacc.2015.06.1328 Stages in the Evolution of MetS and Recommended Therapy by Stage This staging system highlights the progressive nature of MetS, with suggested criteria and recommended therapy for each stage. All therapeutic decisions should be made within the context of absolute risk for end-organ damage. Alt = alternative; BP = blood pressure; CKD = chronic kidney disease; CVD = cardiovascular disease; HDL-C = high-density lipoprotein cholesterol; MetS = metabolic syndrome; NAFLD = nonalcoholic fatty liver disease; OSA = obstructive sleep apnea; TG = triglycerides; WC = waist circumference. Figure Legend:

3. Date of download: 6/25/2016 Copyright © The American College of Cardiology. All rights reserved. From: The CardioMetabolic Health Alliance: Working Toward a New Care Model for the Metabolic Syndrome J Am Coll Cardiol. 2015;66(9):1050-1067. doi:10.1016/j.jacc.2015.06.1328 Integrated Care Model for Patients With MetS: Proceedings of the CardioMetabolic Health Alliance Think Tank Care for patients with MetS should be focused on prevention and disease management within a continuum of individual, community, and public/global health. MetS = metabolic syndrome. Figure Legend: