1. AGENDA – 11/2/15 Take out journals and pick up 2 handouts! Bell-Ringer: Mitosis Mitosis Microviewer lab Cell Cycle and Cancer quick notes

2. Objective Students will recognize that disruptions of the cell cycle can lead to disease, such as cancer.

3. Bell-Ringer 11/2/15: I can identify each phase of mitosis in a picture (out of order)

4. Mitosis Videos http://www.youtube.com/watch?v=DD3IQk nCEdc – Cell Division on Microscopehttp://www.youtube.com/watch?v=DD3IQk nCEdc http://www.youtube.com/watch?v=aDAw2 Zg4IgE – Plant Cell Divisionhttp://www.youtube.com/watch?v=aDAw2 Zg4IgE http://www.youtube.com/watch?v=pOsAbT i9tHw – Mr. W’s Mitosis Raphttp://www.youtube.com/watch?v=pOsAbT i9tHw

5. Section 8.3 Summary – pages 211 - 213 They control when G1 begins, when it stops and S begins, when it stops and G2 begins, etc. Control of Cell Cycle There are enzymes (proteins called cyclins) that control how fast your cells move through the cell cycle.

6. After cytokinesis and the beginning of G1, most cells leave the cell cycle and slip into a resting phase called G 0.

7. Cells will stay in G 0 until there is a reason to divide: -A cell dies -Repair -The organism is growing

8. Section 8.3 Summary – pages 211 - 213 If something goes wrong with the cyclins it can cause cells to hurry through interphase, COMPLETELY SKIP G 0, and divide a lot faster than they should. Control of Cell Cycle

9. Section 8.3 Summary – pages 211 - 213 Cancer are cells that are dividing out of control (uncontrolled mitosis). Control of Cell Cycle Mutations to these enzymes (cyclins) can be caused by environmental factors or certain inheritances.

10. Section 8.3 Summary – pages 211 - 213 A bunch of cancer cells together form masses of tissue called tumors that deprive normal cells of nutrients. CANCER Tumors can be benign or malignant.

11. Metastasize Malignant tumors can spread through the body using the bloodstream.