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Infectious complications and treatment options in intrathecal baclofen delivery systems Themistoklis K, Boutos N, Themistokleous M, Kalyvas AV, Sakas DE Neurosurgery Department, Evaggelismos hospital, University of Athens, Athens, Greece
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Patients and methods 275 patients, from 2001 to 2013 11 (4%) presented with infection 6F/5M ( f/m = 1.2 ) Median age was 49y ( ranging from 33 to 65 y)
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Patients and methods n=6 n=1 n=4 N=6
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mAS Number of patients with infection Patients and methods
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Underlying PathologyNumber of patients with infection Cerebral Palsy5 Multiple Sclerosis3 Traumatic brain Injury3
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Results Infectious agent Staphylococcus aureus: 6 Staphylococcus epidermitis: 4 Pseudomonas aeruginosa: 1 Treatment options Superficial infections (n=6) IV antibiotics (n=4) IV antibiotics, surgical reposition of the pump (contralaterally) due to skin erosion (n=2) Deep infections (n=1) IV antibiotics, surgical reposition of the pump (contralaterally) CNS Infections (n=4) IV and intrathecal antibiotics (n=2) IV and intrathecal antibiotics, surgical removal of the pump and re-implantation after 6 months (n=2)
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Treatment without removal: No interruption of therapy Lower cost Prevention of infections Conclusion
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Thank you for your attention
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