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Printed by www.postersession.com The use of HARRT has significantly decreased the deaths among HIV-infected patients, there has been a shift from AIDs-defining.

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Presentation on theme: "Printed by www.postersession.com The use of HARRT has significantly decreased the deaths among HIV-infected patients, there has been a shift from AIDs-defining."— Presentation transcript:

1 printed by www.postersession.com The use of HARRT has significantly decreased the deaths among HIV-infected patients, there has been a shift from AIDs-defining opportunistic infections to chronic disease. The use of HARRT has significantly decreased the deaths among HIV-infected patients, there has been a shift from AIDs-defining opportunistic infections to chronic disease. Prevalence of HIV in Washington D.C. is at least 3% among people aged over 12 years. This is as high as several African countries according to the District of Columbia’s health department. Prevalence of HIV in Washington D.C. is at least 3% among people aged over 12 years. This is as high as several African countries according to the District of Columbia’s health department. There is no well-defined data to see 30-day readmission data in hospitals serving predominately African American HIV-infected persons. There is no well-defined data to see 30-day readmission data in hospitals serving predominately African American HIV-infected persons. It is believed that those that are non-compliant with their therapy will be more likely to readmitted for the same diagnosis. It is believed that those that are non-compliant with their therapy will be more likely to readmitted for the same diagnosis. 30-day Readmissions in the Post-HAART Era in a Urban Teaching Institution: The Impact of Compliance and ART Use Detron Brown 2, Sohail Ahmed 1, Mary Maneno 2, Monika N. Daftary 2, Jhansi Gajjala 1 1 Howard University Hospital, Division of Infectious Diseases, Washington, DC 1 Howard University Hospital, Division of Infectious Diseases, Washington, DC 2 Howard University, College of Pharmacy, Washington, DC BACKGROUNDBACKGROUNDRESULTSRESULTS REFERENCESREFERENCES Authors of this presentation have the following to disclose concerning possible financial or personal relationships with commercial entities that may have a direct or indirect interest in the subject matter of this presentation: Detron Brown, MPH: Nothing to disclose, Sohail Ahmed, M.D.: Nothing to Disclose Detron Brown, MPH: Nothing to disclose, Sohail Ahmed, M.D.: Nothing to Disclose Monika Daftary, Pharm.D.: Nothing to disclose Mary Maneno, Ph.D.: Nothing to Disclose Monika Daftary, Pharm.D.: Nothing to disclose Mary Maneno, Ph.D.: Nothing to Disclose Jhansi Gajjala, MD.: Nothing to disclose Jhansi Gajjala, MD.: Nothing to disclose METHODSMETHODS DISCLOSURES 1. 1.Palella FJ Jr, Delaney KM, Moorman AC, Loveless MO, Fuhrer J,Satten GA, et al. Declining morbidity and mortality among patients with advanced human immunodeficiency virus infection. N Engl J Med 1998; 338:853–860. 2. 2.CDC. Diagnosis of HIV infection in the United States and dependent areas, 2011. HIV Surveillance report 2013;vol.23. 3. 3.Rates of readmission and death associated with leaving hospital against medical advice: a population-based study CMAJ October 1, 2013 185:1207-1214 4. 4.Palepu, A., Sun, H., Kuyper, L., Schechter, M. T., O'Shaughnessy, M. V. and Anis, A. H. (2003),Predictors of Early Hospital Readmission in HIV- infected Patients with Pneumonia.Journal of General Internal Medicine, 18: 242–247. doi: 10.1046/j.1525 1497.2003.20720.x 5. 5.Shruti K. Gohil, Rupak Datta, Chenghua Cao, Michael J. Phelan, Vinh Nguyen, Armaan A. Rowther, Susan S. Huang. (2015) Impact of Hospital Population Case-Mix, Including Poverty, on Hospital All-Cause and Infection-Related 30-Day Readmission Rates. Clinical Infectious Diseases 61, 1235-1243 153 OBJECTIVESOBJECTIVES To describe HIV infected patients with opportunistic infections and those without opportunistic infections. To describe HIV infected patients with opportunistic infections and those without opportunistic infections. To identify the impact of opportunistic infections along with other factors such as compliance and comorbid conditions on 30-day readmissions. To identify the impact of opportunistic infections along with other factors such as compliance and comorbid conditions on 30-day readmissions. A retrospective chart review was conducted among all HIV- infected patients who were admitted between January 2011 and December 2014. A retrospective chart review was conducted among all HIV- infected patients who were admitted between January 2011 and December 2014. The primary outcome of this study was any 30-day readmission in this patient population The primary outcome of this study was any 30-day readmission in this patient population Other factors evaluated included primary diagnosis, presence of opportunistic infections, socio-demographic variables, compliance on antiviral therapy, length of stay, and prior history of co- morbidities. Other factors evaluated included primary diagnosis, presence of opportunistic infections, socio-demographic variables, compliance on antiviral therapy, length of stay, and prior history of co- morbidities. Descriptive statistics were estimated for all study variables. Bi- variable associations between 30-day readmission and study factors were estimated using chi square, Fisher’s exact and independent t- tests. All analyses was conducted using SAS 9.3 at an alpha of 0.05. Descriptive statistics were estimated for all study variables. Bi- variable associations between 30-day readmission and study factors were estimated using chi square, Fisher’s exact and independent t- tests. All analyses was conducted using SAS 9.3 at an alpha of 0.05. Table 1: Characteristics of all HIV patients who had a hospital admission during the study period (N=1350) Table 2: Factors Associated with 30 day Readmissions LIMITATIONSLIMITATIONS Patient ART compliance variable missing from chart. Patient ART compliance variable missing from chart. CD4 association was assumed at baseline and not measured. CD4 association was assumed at baseline and not measured. CONCLUSION DISCUSSIONDISCUSSION While there continues to be a decrease in re-hospitalizations for opportunistic infections in HIV patients, this is not true for those in Howard University Hospital unique setting. While there continues to be a decrease in re-hospitalizations for opportunistic infections in HIV patients, this is not true for those in Howard University Hospital unique setting. Chronic disease in HIV patients have become a significant predictor of hospitalizations, since ART and better understanding has lengthen the life expectancy of patients with HIV. Chronic disease in HIV patients have become a significant predictor of hospitalizations, since ART and better understanding has lengthen the life expectancy of patients with HIV. The Affordable Care Act recently changed the manner in which they reimburse and it is important to have proper diagnoses in chart to for proper reimbursement. The Affordable Care Act recently changed the manner in which they reimburse and it is important to have proper diagnoses in chart to for proper reimbursement. In conclusion being a male was found to have a significant association with being readmitted within 30-days when compared to females. An additional association was found between having an opportunistic infection and being readmitted with 30 days. There was no significant associated found between insurance type and ART use. While there is information within the literature supports the decrease of readmissions for opportunistic infections with HARRT use, this patient population is still suffering from frequent 30-day readmissions.


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