1. CADTH Symposium 2016

2. The speaker has no financial or other conflicts of interest to report.

3. -Dr. Maureen Trudeau -Medical Oncologist at Sunnybrook Odette Cancer Centre, Professor of Medicine at the University of Toronto. Chair-elect of the Pan Canadian Oncology Expert Drug Review Committee(pERC). -Dr. Kelvin Chan -Medical Oncologist at Sunnybrook Odette Cancer Centre, Assistant Professor at U of T. Clinical lead Drug Reimbursement Programs at CCO. Member of OSSCD, Member of pCODR. -Dr. Stuart Peacock -Professor and Leslie Diamond Chair in Cancer Survivorship and Distinguished Scientist, Faculty of Health Science, Simon Fraser University. Co-Director of ARCC. -Scott Gavura, BScPhm, MBA, RPh. -Director, Provincial Drug Reimbursement Programs at CCO. -Dr. Craig Earle -Medical Oncologist at Sunnybrook Odette Cancer Centre, Director of Health Services Research for CCO and the Ontario Institute for Cancer Research. Professor of Medicine, U of T and Chair OSCCD, Member of pERC

4. Data from general populations of patients collected in a routine fashion: Evaluated against efficacy and cost-effectiveness estimates from the original studies Used to re-evaluate the uptake, benefit, toxicity, or budget impact assumptions Questions around RWE:  How do we collect it?  What infrastructure is needed?  How can provinces collaborate to produce this evidence?  What are the costs of and types of resources needed in collecting and analyzing real world evidence  How will this evidence be used to improve the quality of health care  Strategies to maximize health benefits while minimizing budget impact.

5. -Dr. Maureen Trudeau -Introduction -Dr. Kelvin Chan -Collecting Real World Evidence: HTA’s Perspective -Dr. Stuart Peacock -Real World Evidence: Research Approaches to Health Technology Management -Scott Gavura -Real World Evidence in Cancer Care: A Payer’s Perspective -Dr. Craig Earle -Routinely Collected Data (RDC) and ‘Adaptive’ Drug Reimbursement Arrangements

6. Dr. Kelvin Chan Collecting Real World Evidence: HTA’s Perspective

7. Dr. Stuart Peacock Real World Evidence: Research Approaches to Health Technology Management

8. Scott Gavura Real World Evidence in Cancer Care: A Payer’s Perspective

9. Dr. Craig Earle -Routinely Collected Data (RDC) and ‘Adaptive’ Drug Reimbursement Arrangements

10. Thank-You